Evidence map›Paper›PMID 39694675›Full record

ArticleBMJ open respiratory research2024

Use of metered dose inhalers for bronchodilator responsiveness testing: laboratory practices in Australia and opportunities for carbon footprint reduction.

Michael J Loftus, Jayne Roberts, Nicholas Romeo, Pam Matsas, Karin Leder, Brigitte Borg, Belinda R Miller

Abstract read
In one paragraph

Article in BMJ open respiratory research, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Michael J LoftusHealth and Climate Initiative, Monash University Faculty of Medicine Nursing and Health Sciences, Melbourne, Victoria, Australia michael.loftus@monash.edu.ORCID 0000-0001-6672-0578
Jayne RobertsRespiratory Medicine, Alfred Health, Melbourne, Victoria, Australia.
Nicholas RomeoDepartment of Respiratory Medicine, Northern Health, Melbourne, Victoria, Australia.
Pam MatsasRespiratory Medicine, Alfred Health, Melbourne, Victoria, Australia.
Karin LederHealth and Climate Initiative, Monash University Faculty of Medicine Nursing and Health Sciences, Melbourne, Victoria, Australia.
Brigitte BorgRespiratory Medicine, Alfred Health, Melbourne, Victoria, Australia.
Belinda R MillerRespiratory Medicine, Alfred Health, Melbourne, Victoria, Australia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMetered dose inhalers (MDIs) are important devices for delivering inhaled medications; however, they have an outsized carbon footprint due to their propellant gas. Many short-acting beta-agonist inhalers contain HFA-134a which has a global warming potential >1000 fold higher than carbon dioxide. We aimed to determine the practices around MDI use and disposal within Australia's major lung function testing laboratories and identify the actions that most influence the carbon footprint of bronchodilator responsiveness (BDR) testing.

methodsAustralia's 45 accredited lung function laboratories were invited to participate in an online survey asking about their volume of BDR testing, as well as practices around MDI use such as the number of actuations per BDR test, reuse of MDIs between patients and disposal method. We calculated MDI-associated carbon dioxide equivalent (CO2e) emissions by combining previously published estimates.

results39 laboratories completed the survey. Most laboratories used 4 actuations of salbutamol per BDR test for both adults (27/34, 79.4%) and children (17/20, 85%), but this ranged from 2 to 12. Only three (7.7%) laboratories did not routinely reuse MDIs between patients; however, they all sent their used MDIs for high-temperature incineration. Based on different combinations of observed MDI practices in Australia, we identified a potential sixfold difference in CO2e per 100 BDR tests, from as low as 23.3 kg CO2e up to 166 kg CO2e.

conclusionsWe identified three key practices to reduce the carbon footprint of BDR testing: disposing of MDIs via high-temperature incineration, reducing the number of actuations per BDR test and reusing MDIs between patients.

Indexed as

Bronchodilator AgentsCarbon FootprintMetered Dose InhalersAdministration, InhalationAdultAlbuterolAustraliaCarbon DioxideChildHumansLaboratoriesRespiratory Function TestsSurveys and QuestionnairesAlbuterolBronchodilator AgentsCarbon DioxideInhaler devicesRespiratory Function Test

Identifiers

PMID39694675
PMCPMC11667395

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.