Evidence map›Paper›PMID 39694626›Full record

Observational studyBMJ open gastroenterology2024

Costs of colorectal cancer screening in Sweden: an observational, longitudinal cost description.

Naimi Johansson, Camilla Nystrand, Johannes Blom

Abstract readObservational Study
In one paragraph

Observational study in BMJ open gastroenterology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Naimi JohanssonDepartment of Clinical Science and Education Södersjukhuset, Karolinska Institutet, Stockholm, Sweden naimi.johansson@ki.se.ORCID 0000-0003-2325-5375
Camilla NystrandDepartment of Learning, Informatics, Management & Ethics (LIME), Karolinska Institutet, Stockholm, Sweden.ORCID 0000-0002-9866-1100
Johannes BlomDepartment of Clinical Science and Education Södersjukhuset, Karolinska Institutet, Stockholm, Sweden.ORCID 0000-0002-4938-6640

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveColorectal cancer (CRC) screening programmes have been implemented worldwide, but the evidence of the economic consequences of screening programmes relies on data from short-term trials. The aim of this paper was to describe the costs of CRC screening in a population-based screening programme, using administrative real-world data. Specifically, we aimed to estimate the annual costs of the screening programme and the total costs of the full programme over five consecutive screening rounds.

methodsThe CRC screening programme of Stockholm-Gotland, Sweden, targeted all resident men and women aged 60-69 years for biennial screening. The screening strategy was faecal occult blood testing (FOBT) sent to individuals' home addresses, with a positive test result leading to an invitation to diagnostic colonoscopy. The cost description was conducted with a retrospective, bottom-up costing design from a healthcare perspective using (1) a prevalence-based approach and (2) an incidence-based approach, with two different study samples.

resultsAnnual healthcare costs were estimated using a sample of 124 608 individuals who were affected by the screening programme in 2017. Annual healthcare costs of the screening programme summed up to €273 758 per 10 000 people, equivalent to €27.4 per eligible individual. The sum of costs for colonoscopy procedures was more than two times as high as the costs for FOBT. The costs of the full screening programme were estimated using a cohort of 92 689 individuals who were invited to five consecutive rounds of screening between 2009 and 2021. Total healthcare costs over five screening rounds were €960 654 per 10 000 people, equivalent to €96.1 per individual.

conclusionThe costs of diagnostic colonoscopies for a minority of participants were driving the costs of the CRC screening programme. The ongoing population-based screening programme and high-quality individual level data with long-term follow-up provide the opportunity to thoroughly describe the costs of CRC screening.

Indexed as

Colorectal NeoplasmsEarly Detection of CancerHealth Care CostsAgedColonoscopyCost-Benefit AnalysisFemaleHumansLongitudinal StudiesMaleMass ScreeningMiddle AgedOccult BloodRetrospective StudiesSwedenCOLONOSCOPYCOLORECTAL CANCERCOLORECTAL CANCER SCREENINGCOST-EFFECTIVENESSSCREENING

Identifiers

PMID39694626
PMCPMC11667418

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.