Evidence map›Paper›PMID 39694486›Full record

ArticleInternal medicine (Tokyo, Japan)2025

Prediagnostic Phase of Progressive Supranuclear Palsy in a Longitudinal Epidemiological Study of Dementia and Aging.

Kenta Ishii, Hisashi Takahashi, Misaki Kubota-Hanya, Rei Yasuda, Fumitoshi Niwa, Masaki Kondo, Toshiki Mizuno

Abstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Internal medicine (Tokyo, Japan), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Kenta IshiiDepartment of Neurology, North Medical Center, Kyoto Prefectural University of Medicine, Japan.
Hisashi TakahashiDepartment of Neurology, North Medical Center, Kyoto Prefectural University of Medicine, Japan.
Misaki Kubota-HanyaDepartment of Neurology, North Medical Center, Kyoto Prefectural University of Medicine, Japan.
Rei YasudaDepartment of Neurology, Kyoto Prefectural University of Medicine, Japan.
Fumitoshi NiwaDepartment of General Medicine and Community Healthcare, Kyoto Prefectural University of Medicine, Japan.
Masaki KondoDepartment of Neurology, Kyoto Prefectural University of Medicine, Japan.
Toshiki MizunoDepartment of Neurology, Kyoto Prefectural University of Medicine, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A 63-year-old previously healthy man participated in a longitudinal epidemiologic study of dementia and aging. Although he initially showed no subjective symptoms and a normal motor function, verbal fluency test scores gradually declined, and progressive atrophy of the frontal lobes was observed on magnetic resonance imaging of the head. At 71 years old, progressive supranuclear palsy (PSP) was diagnosed after supranuclear gaze palsy, and gait disturbance developed. This longitudinal epidemiological study suggests that verbal symptoms and mild frontal lobe atrophy may be evident in the premotor phase of PSP.

Indexed as

AgingDementiaSupranuclear Palsy, ProgressiveAgedAtrophyFrontal LobeHumansLongitudinal StudiesMagnetic Resonance ImagingMaleMiddle Agedlongitudinal studyneurodegenerationprodromal symptomprogressive supranuclear palsy

Identifiers

PMID39694486
PMCPMC12287580

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.