ArticleInternational journal of radiation oncology, biology, physics2025
First Retrospective QA of FAST-01 Clinical Treatment Fields Using High-Speed Quantitative Scintillation Imaging.
Article in International journal of radiation oncology, biology, physics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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Who cites it
4 citing papers in PubMed.
- Small dose monitor based on silicon-carbide diodes for FLASH radiotherapy.Medical physics · 2026Article
- High-resolution scintillation imaging for detecting delivery errors in preclinical ultrahigh dose rate proton beam therapy.Medical physics · 2026Article
- Design and characterization of a novel scintillator array for UHDR PBS proton therapy surface dosimetry.Medical physics · 2025Article
- Imaging system for real-time, full-field pulse-by-pulse surface dosimetry of UHDR electron beams.Medical physics · 2025Article
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Authors and funding
10 authors.
Funding
Abstract
purposeTo retrospectively validate the dose and dose rates delivered in FAST-01 clinical trial fields via submillimeter spatial and <0.25 ms temporal resolution scintillation imaging. METHODS AND MATERIALS: An ultrafast intensified CMOS camera (4.5-12 kHz sampling rate) imaged the light response of a scintillator sheet at the treatment isocenter and irradiated by pencil beam scanning proton fields, including FAST-01 clinical fields. Dose and dose rate linearity studies were performed, followed by camera calibration via gafchromic (external beam therapy 3) film. An EDGE diode detector was placed directly under the scintillator at the surface and at a 5 cm depth for comparison with the imaging data and log files. Frame-by-frame analysis of image stacks yielded dose and dose rate maps for each delivery at the surface. Using the percent depth dose curves and 3-dimensional spot profiles, the surface images were projected to a 5 cm depth for comparison with a secondary diode and log file recordings.
resultsCamera response was linear with dose (R
conclusionsThis study provides the first independent validation of dose and dose rate for clinical proton FAST-01 fields at unprecedented spatiotemporal resolution. Owing to the nontrivial dose rate distributions in pencil beam scanning fields, such direct 2-dimensional dose rate mapping will be important in future pretreatment plan quality assurance.
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