Evidence map›Paper›PMID 39694065›Full record

ArticleNature2025

Ancient genomes reveal a deep history of Treponema pallidum in the Americas.

Rodrigo Barquera, T Lesley Sitter, Casey L Kirkpatrick, Darío A Ramirez, Arthur Kocher, Maria A Spyrou, Lourdes R Couoh, Jorge A Talavera-González, Mario Castro, Tanya von Hunnius and 22 more

Abstract read
In one paragraph

Article in Nature, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. A refined phylochronology of the second plague pandemic in Western Eurasia.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  3. Article
  4. Formal description ofInternational journal of systematic and evolutionary microbiology · 2026
    Article
  5. Article
  6. Frontiers in immunology · 2026
    Review
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

32 authors.

Rodrigo Barquera *Max Planck Institute for Evolutionary Anthropology, Leipzig, Germany.ORCID 0000-0003-0518-4518
T Lesley Sitter *Max Planck Institute for Evolutionary Anthropology, Leipzig, Germany.ORCID 0000-0002-7160-6240
Casey L Kirkpatrick *Max Planck Institute for Evolutionary Anthropology, Leipzig, Germany.ORCID 0000-0001-9755-6459
Darío A Ramirez *Instituto de Antropología de Córdoba, Consejo Nacional de Investigaciones Científicas y Técnicas, Universidad Nacional de Córdoba, Museo de Antropologías, Córdoba, Argentina.ORCID 0000-0001-8982-2550
Arthur KocherMax Planck Institute for Evolutionary Anthropology, Leipzig, Germany.
Maria A SpyrouMax Planck Institute for Evolutionary Anthropology, Leipzig, Germany.ORCID 0000-0002-3615-3936
Lourdes R CouohDirección de Antropología Física, Instituto Nacional de Antropología e Historia, Mexico City, Mexico.
Jorge A Talavera-GonzálezDirección de Antropología Física, Instituto Nacional de Antropología e Historia, Mexico City, Mexico.
Mario CastroMuseo Nacional de Historia Natural, Santiago, Chile.
Tanya von HunniusMcMaster University, Department of Anthropology, Hamilton, Ontario, Canada.
Evelyn K GuevaraDepartment of Forensic Medicine, University of Helsinki, Helsinki, Finland.ORCID 0000-0001-5174-1376
W Derek HamiltonScottish Universities Environmental Research Centre, East Kilbride, UK.ORCID 0000-0003-4019-3823
Patrick RobertsDepartment of Coevolution of Land Use and Urbanisation, Max Planck Institute for Geoanthropology, Jena, Germany.ORCID 0000-0002-4403-7548
Erin ScottLaboratory Unit, Max Planck Institute of Geoanthropology, Jena, Germany.
Mariana FabraInstituto de Antropología de Córdoba, Consejo Nacional de Investigaciones Científicas y Técnicas, Universidad Nacional de Córdoba, Museo de Antropologías, Córdoba, Argentina.
Gabriela V Da PeñaConsejo Nacional de Investigaciones Científicas y Técnicas, Museo de Ciencias Naturales y Antropológicas Juan C. Moyano, Mendoza, Argentina.ORCID 0000-0003-3410-3027
Aryel PachecoBioarchaeology Research Group, Durham University, Durham, UK.ORCID 0000-0002-5569-2281
Mónica RodriguezIndependent researcher, Santiago, Chile.
Eugenio AspillagaDepartment of Anthropology, University of Chile, Santiago, Chile.
Anthi TiliakouMax Planck Institute for Evolutionary Anthropology, Leipzig, Germany.
Elizabeth A NelsonMax Planck Institute for Evolutionary Anthropology, Leipzig, Germany.
Karen L GiffinMax Planck Institute for Evolutionary Anthropology, Leipzig, Germany.
Raffaela A BiancoMax Planck Institute for Evolutionary Anthropology, Leipzig, Germany.ORCID 0009-0004-6087-8031
Adam B RohrlachMax Planck Institute for Evolutionary Anthropology, Leipzig, Germany.ORCID 0000-0002-4204-5018
María de Los Ángeles García MartínezDirección de Salvamento Arqueológico, Instituto Nacional de Antropología e Historia, Mexico City, Mexico.
Fabiola A Ballesteros SolísDirección de Antropología Física, Instituto Nacional de Antropología e Historia, Mexico City, Mexico.
Antti SajantilaDepartment of Forensic Medicine, University of Helsinki, Helsinki, Finland.ORCID 0000-0003-4117-5248
Shelley R SaundersMcMaster University, Department of Anthropology, Hamilton, Ontario, Canada.
Rodrigo NoresInstituto de Antropología de Córdoba, Consejo Nacional de Investigaciones Científicas y Técnicas, Universidad Nacional de Córdoba, Museo de Antropologías, Córdoba, Argentina.ORCID 0000-0002-9153-0626
Alexander HerbigMax Planck Institute for Evolutionary Anthropology, Leipzig, Germany.ORCID 0000-0003-1176-1166
Johannes KrauseMax Planck Institute for Evolutionary Anthropology, Leipzig, Germany. krause@eva.mpg.de.ORCID 0000-0001-9144-3920
Kirsten I BosMax Planck Institute for Evolutionary Anthropology, Leipzig, Germany. kirsten_bos@eva.mpg.de.ORCID 0000-0003-2937-3006

Funding

Kone Foundation, the Faculty of Medicine and the Faculty of Biological and Environmental Sciences at the University of HelsinkiMax Planck Society, European Research Council (ERC) under the European Union’s Horizon 2020 research and innovation programme
6 · The paper itself

Abstract

Human treponemal infections are caused by a family of closely related Treponema pallidum that give rise to the diseases yaws, bejel, pinta and, most notably, syphilis

Indexed as

DNA, AncientEvolution, MolecularGenome, BacterialSyphilisTreponema pallidumAmericasHumansPhylogenyYawsDNA, Ancient

Identifiers

PMID39694065
PMCPMC11964931

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.