ArticleNeurology2025
Sleep Disordered Breathing and Subsequent Neuroimaging Markers of Brain Health in Hispanic/Latino Adults.
Abstract readMulticenter Study
In one paragraph
Article in Neurology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Sleep apnea in REM sleep as an amplifier of vascular contributions to Alzheimer's disease.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2026Review
- Cognition and psychomotor vigilance in treated sleep apnea patients with and without daytime sleepiness: the MAGNETO study.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
17 authors.
Alberto R RamosFrom the Department of Neurology (A.R.R., C.A., S.K.), Miller School of Medicine, University of Miami, FL; University of California, San Diego (K.A.G., H.M.G.); Wayne State University (W.T.), Detroit, MI; Institute of Minority Health Research (M.D.), University of Illinois College of Medicine, Chicago; Department of Psychology (L.C.G., A.M.S., G.A.T.), San Diego State University, CA; Albert Einstein College of Medicine (C.I.I., R.B.L.), New York, NY; Department of Medicine (S.R.P.), University of Pittsburgh School of Medicine, PA; Brigham Women's Hospital (S.R.), Harvard School of Medicine, Boston, MA; Gillings School of Global Public Health (D.S.-A.), University of North Carolina, Chapel Hill; Department of Neurology and Rehabilitation (F.D.T.), University of Illinois College of Medicine, Chicago; and University of California, Davis (C.S.D.).ORCID 0000-0002-9861-6609
Christian AgudeloFrom the Department of Neurology (A.R.R., C.A., S.K.), Miller School of Medicine, University of Miami, FL; University of California, San Diego (K.A.G., H.M.G.); Wayne State University (W.T.), Detroit, MI; Institute of Minority Health Research (M.D.), University of Illinois College of Medicine, Chicago; Department of Psychology (L.C.G., A.M.S., G.A.T.), San Diego State University, CA; Albert Einstein College of Medicine (C.I.I., R.B.L.), New York, NY; Department of Medicine (S.R.P.), University of Pittsburgh School of Medicine, PA; Brigham Women's Hospital (S.R.), Harvard School of Medicine, Boston, MA; Gillings School of Global Public Health (D.S.-A.), University of North Carolina, Chapel Hill; Department of Neurology and Rehabilitation (F.D.T.), University of Illinois College of Medicine, Chicago; and University of California, Davis (C.S.D.).ORCID 0000-0001-8957-8615
Kevin A GonzalezFrom the Department of Neurology (A.R.R., C.A., S.K.), Miller School of Medicine, University of Miami, FL; University of California, San Diego (K.A.G., H.M.G.); Wayne State University (W.T.), Detroit, MI; Institute of Minority Health Research (M.D.), University of Illinois College of Medicine, Chicago; Department of Psychology (L.C.G., A.M.S., G.A.T.), San Diego State University, CA; Albert Einstein College of Medicine (C.I.I., R.B.L.), New York, NY; Department of Medicine (S.R.P.), University of Pittsburgh School of Medicine, PA; Brigham Women's Hospital (S.R.), Harvard School of Medicine, Boston, MA; Gillings School of Global Public Health (D.S.-A.), University of North Carolina, Chapel Hill; Department of Neurology and Rehabilitation (F.D.T.), University of Illinois College of Medicine, Chicago; and University of California, Davis (C.S.D.).
Wassim TarrafFrom the Department of Neurology (A.R.R., C.A., S.K.), Miller School of Medicine, University of Miami, FL; University of California, San Diego (K.A.G., H.M.G.); Wayne State University (W.T.), Detroit, MI; Institute of Minority Health Research (M.D.), University of Illinois College of Medicine, Chicago; Department of Psychology (L.C.G., A.M.S., G.A.T.), San Diego State University, CA; Albert Einstein College of Medicine (C.I.I., R.B.L.), New York, NY; Department of Medicine (S.R.P.), University of Pittsburgh School of Medicine, PA; Brigham Women's Hospital (S.R.), Harvard School of Medicine, Boston, MA; Gillings School of Global Public Health (D.S.-A.), University of North Carolina, Chapel Hill; Department of Neurology and Rehabilitation (F.D.T.), University of Illinois College of Medicine, Chicago; and University of California, Davis (C.S.D.).ORCID 0000-0001-8888-7918
Martha DaviglusFrom the Department of Neurology (A.R.R., C.A., S.K.), Miller School of Medicine, University of Miami, FL; University of California, San Diego (K.A.G., H.M.G.); Wayne State University (W.T.), Detroit, MI; Institute of Minority Health Research (M.D.), University of Illinois College of Medicine, Chicago; Department of Psychology (L.C.G., A.M.S., G.A.T.), San Diego State University, CA; Albert Einstein College of Medicine (C.I.I., R.B.L.), New York, NY; Department of Medicine (S.R.P.), University of Pittsburgh School of Medicine, PA; Brigham Women's Hospital (S.R.), Harvard School of Medicine, Boston, MA; Gillings School of Global Public Health (D.S.-A.), University of North Carolina, Chapel Hill; Department of Neurology and Rehabilitation (F.D.T.), University of Illinois College of Medicine, Chicago; and University of California, Davis (C.S.D.).ORCID 0000-0002-6791-8727
Linda C GalloFrom the Department of Neurology (A.R.R., C.A., S.K.), Miller School of Medicine, University of Miami, FL; University of California, San Diego (K.A.G., H.M.G.); Wayne State University (W.T.), Detroit, MI; Institute of Minority Health Research (M.D.), University of Illinois College of Medicine, Chicago; Department of Psychology (L.C.G., A.M.S., G.A.T.), San Diego State University, CA; Albert Einstein College of Medicine (C.I.I., R.B.L.), New York, NY; Department of Medicine (S.R.P.), University of Pittsburgh School of Medicine, PA; Brigham Women's Hospital (S.R.), Harvard School of Medicine, Boston, MA; Gillings School of Global Public Health (D.S.-A.), University of North Carolina, Chapel Hill; Department of Neurology and Rehabilitation (F.D.T.), University of Illinois College of Medicine, Chicago; and University of California, Davis (C.S.D.).ORCID 0000-0002-3678-5888
Carmen I IsasiFrom the Department of Neurology (A.R.R., C.A., S.K.), Miller School of Medicine, University of Miami, FL; University of California, San Diego (K.A.G., H.M.G.); Wayne State University (W.T.), Detroit, MI; Institute of Minority Health Research (M.D.), University of Illinois College of Medicine, Chicago; Department of Psychology (L.C.G., A.M.S., G.A.T.), San Diego State University, CA; Albert Einstein College of Medicine (C.I.I., R.B.L.), New York, NY; Department of Medicine (S.R.P.), University of Pittsburgh School of Medicine, PA; Brigham Women's Hospital (S.R.), Harvard School of Medicine, Boston, MA; Gillings School of Global Public Health (D.S.-A.), University of North Carolina, Chapel Hill; Department of Neurology and Rehabilitation (F.D.T.), University of Illinois College of Medicine, Chicago; and University of California, Davis (C.S.D.).ORCID 0000-0003-2700-9593
Sonya KaurFrom the Department of Neurology (A.R.R., C.A., S.K.), Miller School of Medicine, University of Miami, FL; University of California, San Diego (K.A.G., H.M.G.); Wayne State University (W.T.), Detroit, MI; Institute of Minority Health Research (M.D.), University of Illinois College of Medicine, Chicago; Department of Psychology (L.C.G., A.M.S., G.A.T.), San Diego State University, CA; Albert Einstein College of Medicine (C.I.I., R.B.L.), New York, NY; Department of Medicine (S.R.P.), University of Pittsburgh School of Medicine, PA; Brigham Women's Hospital (S.R.), Harvard School of Medicine, Boston, MA; Gillings School of Global Public Health (D.S.-A.), University of North Carolina, Chapel Hill; Department of Neurology and Rehabilitation (F.D.T.), University of Illinois College of Medicine, Chicago; and University of California, Davis (C.S.D.).
Richard B LiptonFrom the Department of Neurology (A.R.R., C.A., S.K.), Miller School of Medicine, University of Miami, FL; University of California, San Diego (K.A.G., H.M.G.); Wayne State University (W.T.), Detroit, MI; Institute of Minority Health Research (M.D.), University of Illinois College of Medicine, Chicago; Department of Psychology (L.C.G., A.M.S., G.A.T.), San Diego State University, CA; Albert Einstein College of Medicine (C.I.I., R.B.L.), New York, NY; Department of Medicine (S.R.P.), University of Pittsburgh School of Medicine, PA; Brigham Women's Hospital (S.R.), Harvard School of Medicine, Boston, MA; Gillings School of Global Public Health (D.S.-A.), University of North Carolina, Chapel Hill; Department of Neurology and Rehabilitation (F.D.T.), University of Illinois College of Medicine, Chicago; and University of California, Davis (C.S.D.).ORCID 0000-0003-2652-2897
Sanjay R PatelFrom the Department of Neurology (A.R.R., C.A., S.K.), Miller School of Medicine, University of Miami, FL; University of California, San Diego (K.A.G., H.M.G.); Wayne State University (W.T.), Detroit, MI; Institute of Minority Health Research (M.D.), University of Illinois College of Medicine, Chicago; Department of Psychology (L.C.G., A.M.S., G.A.T.), San Diego State University, CA; Albert Einstein College of Medicine (C.I.I., R.B.L.), New York, NY; Department of Medicine (S.R.P.), University of Pittsburgh School of Medicine, PA; Brigham Women's Hospital (S.R.), Harvard School of Medicine, Boston, MA; Gillings School of Global Public Health (D.S.-A.), University of North Carolina, Chapel Hill; Department of Neurology and Rehabilitation (F.D.T.), University of Illinois College of Medicine, Chicago; and University of California, Davis (C.S.D.).ORCID 0000-0002-9142-5172
Susan RedlineFrom the Department of Neurology (A.R.R., C.A., S.K.), Miller School of Medicine, University of Miami, FL; University of California, San Diego (K.A.G., H.M.G.); Wayne State University (W.T.), Detroit, MI; Institute of Minority Health Research (M.D.), University of Illinois College of Medicine, Chicago; Department of Psychology (L.C.G., A.M.S., G.A.T.), San Diego State University, CA; Albert Einstein College of Medicine (C.I.I., R.B.L.), New York, NY; Department of Medicine (S.R.P.), University of Pittsburgh School of Medicine, PA; Brigham Women's Hospital (S.R.), Harvard School of Medicine, Boston, MA; Gillings School of Global Public Health (D.S.-A.), University of North Carolina, Chapel Hill; Department of Neurology and Rehabilitation (F.D.T.), University of Illinois College of Medicine, Chicago; and University of California, Davis (C.S.D.).ORCID 0000-0002-6585-1610
Daniela Sostres-AlvarezFrom the Department of Neurology (A.R.R., C.A., S.K.), Miller School of Medicine, University of Miami, FL; University of California, San Diego (K.A.G., H.M.G.); Wayne State University (W.T.), Detroit, MI; Institute of Minority Health Research (M.D.), University of Illinois College of Medicine, Chicago; Department of Psychology (L.C.G., A.M.S., G.A.T.), San Diego State University, CA; Albert Einstein College of Medicine (C.I.I., R.B.L.), New York, NY; Department of Medicine (S.R.P.), University of Pittsburgh School of Medicine, PA; Brigham Women's Hospital (S.R.), Harvard School of Medicine, Boston, MA; Gillings School of Global Public Health (D.S.-A.), University of North Carolina, Chapel Hill; Department of Neurology and Rehabilitation (F.D.T.), University of Illinois College of Medicine, Chicago; and University of California, Davis (C.S.D.).ORCID 0000-0002-3226-6140
Ariana M StickelFrom the Department of Neurology (A.R.R., C.A., S.K.), Miller School of Medicine, University of Miami, FL; University of California, San Diego (K.A.G., H.M.G.); Wayne State University (W.T.), Detroit, MI; Institute of Minority Health Research (M.D.), University of Illinois College of Medicine, Chicago; Department of Psychology (L.C.G., A.M.S., G.A.T.), San Diego State University, CA; Albert Einstein College of Medicine (C.I.I., R.B.L.), New York, NY; Department of Medicine (S.R.P.), University of Pittsburgh School of Medicine, PA; Brigham Women's Hospital (S.R.), Harvard School of Medicine, Boston, MA; Gillings School of Global Public Health (D.S.-A.), University of North Carolina, Chapel Hill; Department of Neurology and Rehabilitation (F.D.T.), University of Illinois College of Medicine, Chicago; and University of California, Davis (C.S.D.).ORCID 0000-0002-6312-2377
Fernando D TestaiFrom the Department of Neurology (A.R.R., C.A., S.K.), Miller School of Medicine, University of Miami, FL; University of California, San Diego (K.A.G., H.M.G.); Wayne State University (W.T.), Detroit, MI; Institute of Minority Health Research (M.D.), University of Illinois College of Medicine, Chicago; Department of Psychology (L.C.G., A.M.S., G.A.T.), San Diego State University, CA; Albert Einstein College of Medicine (C.I.I., R.B.L.), New York, NY; Department of Medicine (S.R.P.), University of Pittsburgh School of Medicine, PA; Brigham Women's Hospital (S.R.), Harvard School of Medicine, Boston, MA; Gillings School of Global Public Health (D.S.-A.), University of North Carolina, Chapel Hill; Department of Neurology and Rehabilitation (F.D.T.), University of Illinois College of Medicine, Chicago; and University of California, Davis (C.S.D.).ORCID 0000-0002-7355-4915
Gregory A TalaveraFrom the Department of Neurology (A.R.R., C.A., S.K.), Miller School of Medicine, University of Miami, FL; University of California, San Diego (K.A.G., H.M.G.); Wayne State University (W.T.), Detroit, MI; Institute of Minority Health Research (M.D.), University of Illinois College of Medicine, Chicago; Department of Psychology (L.C.G., A.M.S., G.A.T.), San Diego State University, CA; Albert Einstein College of Medicine (C.I.I., R.B.L.), New York, NY; Department of Medicine (S.R.P.), University of Pittsburgh School of Medicine, PA; Brigham Women's Hospital (S.R.), Harvard School of Medicine, Boston, MA; Gillings School of Global Public Health (D.S.-A.), University of North Carolina, Chapel Hill; Department of Neurology and Rehabilitation (F.D.T.), University of Illinois College of Medicine, Chicago; and University of California, Davis (C.S.D.).ORCID 0000-0001-5360-1107
Hector M GonzalezFrom the Department of Neurology (A.R.R., C.A., S.K.), Miller School of Medicine, University of Miami, FL; University of California, San Diego (K.A.G., H.M.G.); Wayne State University (W.T.), Detroit, MI; Institute of Minority Health Research (M.D.), University of Illinois College of Medicine, Chicago; Department of Psychology (L.C.G., A.M.S., G.A.T.), San Diego State University, CA; Albert Einstein College of Medicine (C.I.I., R.B.L.), New York, NY; Department of Medicine (S.R.P.), University of Pittsburgh School of Medicine, PA; Brigham Women's Hospital (S.R.), Harvard School of Medicine, Boston, MA; Gillings School of Global Public Health (D.S.-A.), University of North Carolina, Chapel Hill; Department of Neurology and Rehabilitation (F.D.T.), University of Illinois College of Medicine, Chicago; and University of California, Davis (C.S.D.).
Charles S DecarliFrom the Department of Neurology (A.R.R., C.A., S.K.), Miller School of Medicine, University of Miami, FL; University of California, San Diego (K.A.G., H.M.G.); Wayne State University (W.T.), Detroit, MI; Institute of Minority Health Research (M.D.), University of Illinois College of Medicine, Chicago; Department of Psychology (L.C.G., A.M.S., G.A.T.), San Diego State University, CA; Albert Einstein College of Medicine (C.I.I., R.B.L.), New York, NY; Department of Medicine (S.R.P.), University of Pittsburgh School of Medicine, PA; Brigham Women's Hospital (S.R.), Harvard School of Medicine, Boston, MA; Gillings School of Global Public Health (D.S.-A.), University of North Carolina, Chapel Hill; Department of Neurology and Rehabilitation (F.D.T.), University of Illinois College of Medicine, Chicago; and University of California, Davis (C.S.D.).ORCID 0000-0003-1914-2693
Funding
UCSD Shiley-Marcos Alzheimer's Disease Research Center P30P30AG062429 · NIA · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI JAMES B BREWER · 2019 to 2026
$34.9MPilot Program CoreP30ES027792 · NIEHS · UNIVERSITY OF CHICAGO · PI Gokhan M. Mutlu, Gail S Prins · 2017 to 2026
$13.6MMiami Clinical and Translational Science Institute K12 ProgramK12TR004555 · NCATS · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI ALESSIA FORNONI, Tatjana Rundek · 2023 to 2026
$3.0MUCSD Leading the Advancement of Underrepresented Neuroscientists for Change (LAUNCH) Faculty Development ProgramR25NS117367 · NINDS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Victoria B Risbrough, Joann Trejo · 2020 to 2026
$1.6MNCATS NIH HHS K12 TR004555NIA NIH HHS P30 AG062429NIEHS NIH HHS P30 ES027792NINDS NIH HHS R25 NS117367
Abstract
BACKGROUND AND
objectivesSleep disordered breathing (SDB) is a risk factor of stroke and Alzheimer disease and related dementias (ADRDs). Hispanic/Latino adults have higher risk of SDB and ADRDs, which emphasizes the need to better understand the association between SDB and brain health. Furthermore, results on SDB and brain aging are mixed, and there are limited data for Hispanic/Latino adults. The main goal of this study is to assess the association between SDB and brain MRI measures in a diverse Hispanic/Latino population.
methodsThe Hispanic Community Health Study/Study of Latinos (HCHS/SOL) is a community-based prospective cohort multisite (Bronx, Chicago, Miami, San Diego) study of diverse Hispanic/Latino adults in the United States. Participants underwent 1 night of unsupervised home testing with a sleep apnea test device at baseline. The SOL-Investigation of Neurocognitive Aging MRI, an ancillary study, recruited 2,667 HCHS/SOL participants (35-85 years) who underwent neuroimaging approximately 10 years after baseline sleep assessment. The main exposure was the respiratory event index (REI, 3% desaturation). Secondary exposures encompassed measures of oxygen saturation. Main outcomes included total brain, gray matter, white matter hyperintensity (WMH), and hippocampal volumes. Survey linear regression models were used to determine associations between SDB and brain MRI measures.
resultsThe mean age was 67.6 years, with a body mass index of 29.7, and 58.3% were female. We found that increased REI was associated with larger hippocampal volumes ( DISCUSSION: We found that SDB and worse oxygenation during sleep were linked to larger hippocampal volumes. These results underscore the complex relationships between sleep health and brain aging and warrant longitudinal follow-up, starting in middle age or earlier.
Indexed as
BrainHispanic or LatinoMagnetic Resonance ImagingSleep Apnea SyndromesAdultAgedAged, 80 and overCohort StudiesFemaleHumansMaleMiddle AgedNeuroimagingProspective Studies
Identifiers
What OpenQuestion holds
Textmetadata
Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.