ArticleScience translational medicine2024
IFN-γ-producing T
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In one paragraph
Article in Science translational medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.
0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
26 citing papers in PubMed.
- Immune Hallmarks of Recurrent Immune Checkpoint Inhibitor-Mediated Inflammatory Arthritis.Cancer immunology research · 2026Article
- Mechanisms of Chinese Medicines for Primary Sjögren's Syndrome: A Review.Chinese journal of integrative medicine · 2026Review
- T Cell-Derived IFN-γ Activates Ferroptosis in Lacrimal Luminal Ductal Cells via JAK-STAT Signaling in Sjögren's Disease-Related Dry Eye.Investigative ophthalmology & visual science · 2026Article
- Mitochondrial RNA-Type I Interferon Axis in Sjögren's Disease: Molecular Mechanisms and Translational Implications.International journal of molecular sciences · 2026Review
- RAS P21 Protein Activator 3 finetunes Type I immunity by limiting HCK-mediated STAT4 phosphorylation.Nature communications · 2026Article
- Overlap syndrome between sarcoidosis and Sjögren's disease presenting as hypopituitarism: case report and review of literature.Endocrine journal · 2026Review
- Single-Cell RNA Sequencing Revealed the Role of Interferon-Gamma Related Genes in Primary Sjögren's Syndrome.Journal of cellular and molecular medicine · 2026Article
- Agomelatine for Sjögren's syndrome: a study on its therapeutic effects and mechanisms.Inflammopharmacology · 2026Article
- Dysregulated calcium signaling underlies hyposalivation and microbial dysbiosis in Down syndrome.Cell reports · 2026Article
- Single-cell profiling reveals clonal CD8Inflammation research : official journal of the European Histamine Research Society ... [et al.] · 2026Article
- Ocular IL-1α/IFN-γ Delay the Corneal Wound Healing in Rheumatoid Arthritis Through Mitochondrial Dysfunction and NLRP3 Inflammasome Activation.Investigative ophthalmology & visual science · 2026Article
- Molecular Insights into Oral Manifestations in Sjögren's Disease.International journal of molecular sciences · 2026Review
- Tracheobronchial ulcers caused byThe Journal of international medical research · 2026Review
- Regulatory T cells in primary sjögren disease: regulatory mechanisms and therapeutic prospects.Frontiers in immunology · 2026Review
- Platelet-to-lymphocyte ratio: a predictive biomarker for exocrine gland involvement in Sjögren disease.Advances in rheumatology (London, England) · 2025Article
- TScience advances · 2025Article
- The Immunobiology of Dry Eye Disease: A Review of the Pathogenesis, Regulation and Therapeutic Implications.International journal of molecular sciences · 2025Review
- Targeting myeloid differentiation protein 2 ameliorates rheumatoid arthritis by inhibiting inflammation and ferroptosis via MAPK and NF-κB signaling pathways.Journal of molecular medicine (Berlin, Germany) · 2025Article
- Machine learning approach to single cell transcriptomic analysis of Sjogren's disease reveals altered activation states of B and T lymphocytes.Journal of autoimmunity · 2025Article
- The role of fatty acid metabolism on B cells and B cell-related autoimmune diseases.Inflammation research : official journal of the European Histamine Research Society ... [et al.] · 2025Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
15 authors.
Yin-Hu WangDepartment of Pathology, New York University Grossman School of Medicine, New York, NY 10016, USA.ORCID 0000-0002-3637-8852
Wenyi LiDepartment of Pathology, New York University Grossman School of Medicine, New York, NY 10016, USA.ORCID 0000-0002-5436-1317
Maxwell McDermottDepartment of Pathology, New York University Grossman School of Medicine, New York, NY 10016, USA.ORCID 0009-0005-9503-0556
Ga-Yeon SonDepartment of Molecular Pathobiology, New York University College of Dentistry, New York, NY 10010, USA.ORCID 0000-0002-3680-9421
George MaitiDepartment of Ophthalmology, New York University Grossman School of Medicine, New York, NY 10016, USA.ORCID 0000-0002-6701-5499
Fang ZhouDepartment of Pathology, New York University Grossman School of Medicine, New York, NY 10016, USA.ORCID 0000-0002-5542-2994
Anthony Y TaoDepartment of Pathology, New York University Grossman School of Medicine, New York, NY 10016, USA.ORCID 0000-0003-0978-2769
Dimitrius RaphaelDepartment of Pathology, New York University Grossman School of Medicine, New York, NY 10016, USA.ORCID 0000-0003-1064-3010
Andre L MoreiraDepartment of Pathology, New York University Grossman School of Medicine, New York, NY 10016, USA.ORCID 0000-0003-1857-3774
Boheng ShenDepartment of Pathology, New York University Grossman School of Medicine, New York, NY 10016, USA.ORCID 0009-0003-0066-283X
Martin VaethDepartment of Pathology, New York University Grossman School of Medicine, New York, NY 10016, USA.ORCID 0000-0001-8974-7052
Bettina NadorpDepartment of Pathology, New York University Grossman School of Medicine, New York, NY 10016, USA.ORCID 0000-0003-1974-8425
Shukti ChakravartiDepartment of Pathology, New York University Grossman School of Medicine, New York, NY 10016, USA.ORCID 0000-0001-7543-1903
Rodrigo S LacruzDepartment of Molecular Pathobiology, New York University College of Dentistry, New York, NY 10010, USA.ORCID 0000-0002-0776-6143
Stefan FeskeDepartment of Pathology, New York University Grossman School of Medicine, New York, NY 10016, USA.ORCID 0000-0001-5431-8178
Funding
Sjögren's International Collaborative Clinical Alliance Next Generation Studies (SICCA-NextGen)U01DE028891 · NIDCR · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI SHIBOSKI, CAROLINE HELENE · 2020 to 2024
$4.0MCa2+ signaling via SOCE in the pathogenesis of Sjögren’s syndromeR01DE027981 · NIDCR · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI FESKE, STEFAN, LACRUZ, RODRIGO S. · 2019 to 2023
$2.7MExtracellular matrix proteoglycans regulate toll-like receptors 4 and 9 - Equipment SupplementR01EY030917 · NEI · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI CHAKRAVARTI, SHUKTI · 2020 to 2023
$1.8MThe role of ion channels and transporters in B cell functionF30AI164803 · NIAID · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI TAO, ANTHONY · 2022 to 2024
$158kINTERNATIONAL RESEARCH REGISTRY NETWORK FOR SJOGERNS SYNDROME-268032636N01DE032636 · NIDCR · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI GREENSPAN, JOHN · 2005 to 2006
–NEI NIH HHS R01 EY030917NIAID NIH HHS F30 AI164803NIDCR NIH HHS N01 DE032636NIDCR NIH HHS R01 DE027981NIDCR NIH HHS U01 DE028891
Abstract
Sjögren's disease (SjD) is an autoimmune disorder characterized by progressive salivary and lacrimal gland dysfunction, inflammation, and destruction, as well as extraglandular manifestations. SjD is associated with autoreactive B and T cells, but its pathophysiology remains incompletely understood. Abnormalities in regulatory T (T
Indexed as
Interferon-gammaSjogren's SyndromeTh1 CellsT-Lymphocytes, RegulatoryAnimalsHumansLacrimal ApparatusMiceSignal TransductionStromal Interaction Molecule 1Stromal Interaction Molecule 2Interferon-gammaStromal Interaction Molecule 1Stromal Interaction Molecule 2
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.