Evidence map›Paper›PMID 39693349›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2024

Nutrient colimitation is a quantitative, dynamic property of microbial populations.

Noelle A Held, Aswin Krishna, Donat Crippa, Rachana Rao Battaje, Alexander J Devaux, Anastasia Dragan, Michael Manhart

Abstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Localized nutrient colimitation of phytoplankton growth rates across the subtropical South Pacific Ocean.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  5. Nutrient colimitation is a quantitative, dynamic property of microbial populations.Proceedings of the National Academy of Sciences of the United States of America · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Noelle A HeldDepartment of Environmental Systems Science, Swiss Federal Institute of Technology (ETH) Zurich, Zurich 8006, Switzerland.ORCID 0000-0003-1073-0851
Aswin KrishnaDepartment of Environmental Systems Science, Swiss Federal Institute of Technology (ETH) Zurich, Zurich 8006, Switzerland.ORCID 0009-0007-5973-7890
Donat CrippaDepartment of Environmental Systems Science, Swiss Federal Institute of Technology (ETH) Zurich, Zurich 8006, Switzerland.ORCID 0009-0007-1777-6533
Rachana Rao BattajeCenter for Advanced Biotechnology and Medicine, Rutgers University, Piscataway, NJ 08854.ORCID 0009-0009-3387-7507
Alexander J DevauxDepartment of Biological Sciences, Marine & Environmental Biology Section, University of Southern California, Los Angeles, CA 90089.
Anastasia DraganDepartment of Environmental Systems Science, Swiss Federal Institute of Technology (ETH) Zurich, Zurich 8006, Switzerland.
Michael ManhartDepartment of Environmental Systems Science, Swiss Federal Institute of Technology (ETH) Zurich, Zurich 8006, Switzerland.ORCID 0000-0003-3791-9056

Funding

Non-US Government Research Support type
6 · The paper itself

Abstract

Resource availability dictates how fast and how much microbial populations grow. Quantifying the relationship between microbial growth and resource concentrations makes it possible to promote, inhibit, and predict microbial activity. Microbes require many resources, including macronutrients (e.g., carbon and nitrogen), micronutrients (e.g., metals), and complex nutrients like vitamins and amino acids. When multiple resources are scarce, as frequently occurs in nature, microbes may experience resource colimitation in which more than one resource simultaneously limits growth. Despite growing evidence for colimitation, the data are difficult to interpret and compare due to a lack of quantitative measures of colimitation and systematic tests of resource conditions. We hypothesize that microbes experience a continuum of nutrient limitation states and that nutrient colimitation is common in the laboratory and in nature. To address this, we develop a quantitative theory of resource colimitation that captures the range of possible limitation states and describes how they can change dynamically with resource conditions. We apply this approach to clonal populations of

Indexed as

Escherichia coliNutrientsCarbonModels, BiologicalNitrogenCarbonNitrogenNutrientsbiogeochemistrycolimitationmarine microbesmicrobial growthnutrient limitation

Identifiers

PMID39693349
PMCPMC11670248

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.