Evidence map›Paper›PMID 39693202›Full record

ArticleHuman vaccines & immunotherapeutics2024

Optimal implementation of an Ontario nirsevimab program for respiratory syncytial virus (RSV) prophylaxis: Recommendations from a provincial RSV expert panel.

Bosco Paes, Vivien Brown, Erin Courtney, Erin Fleischer, Fiona Guy, Eddy Lau, Allan Mills, Julie Toole, Meagan Bardan, Cynthia Wong and 2 more

Abstract read
In one paragraph

Article in Human vaccines & immunotherapeutics, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Bosco PaesDepartment of Pediatrics, McMaster University & Hamilton Health Sciences, Hamilton, ON, Canada.ORCID 0000-0002-3308-2706
Vivien BrownDepartment of Family & Community Medicine, University of Toronto, Toronto, ON, Canada.
Erin CourtneyDepartment of Nursing, Lambton College, London, ON, Canada.
Erin FleischerChildren's Hospital, London Health Sciences Centre, London, ON, Canada.
Fiona GuyDepartment of Pediatrics, McMaster Children's Hospital, Hamilton, ON, Canada.
Eddy LauDepartment of Paediatrics, University of Toronto, Toronto, ON, Canada.
Allan MillsPharmacy Department, Trillium Health Partners, Mississauga, ON, Canada.
Julie TooleAssociation of Ontario Midwives, Toronto, ON, Canada.
Meagan BardanDepartment of Medical Affairs, Sanofi, Toronto, ON, Canada.
Cynthia WongDepartment of Medical Affairs, Sanofi, Toronto, ON, Canada.
Gary LamDepartment of Medical Affairs, Sanofi, Toronto, ON, Canada.
Graeme N SmithDepartment of Obstetrics & Gynecology, Queen's University, Kingston, ON, Canada.ORCID 0000-0002-3128-4523

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In June 2024, a group of 12 experts in the respiratory syncytial virus (RSV) field representing a cross-section of healthcare provider types who treat and care for pregnant individuals and infants, assembled to discuss the implementation of a broad infant prophylaxis program with nirsevimab in Ontario. To gain insight on potential best practices founded on the experiences of other jurisdictions, the meeting comprised a review of the 2023/2024 RSV season programs in Spain, France, and the United States that implemented nirsevimab prophylaxis. The impact of nirsevimab in reducing severe RSV disease among infants during the first RSV season was assessed including the implications on hospital resources and healthcare system costs. The panel also reviewed the results of a 2024 online survey of healthcare providers in the province to gain insight into how the program should be implemented in Ontario to facilitate uptake in infants born during and before the onset of the RSV season. The resulting discussion led to panel consensus on several recommendations to help inform programmatic decisions regarding how nirsevimab should be administered to infants in Ontario to achieve optimal uptake and best protection against this potentially devastating infectious disease.

Indexed as

Antiviral AgentsRespiratory Syncytial Virus InfectionsFemaleHumansInfantOntarioPregnancyRespiratory Syncytial Virus, HumanAntiviral AgentsCanadainfantsnirsevimabpassive immunizationprogram deliverypublic healthRespiratory syncytial virus (RSV)

Identifiers

PMID39693202
PMCPMC11789722

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.