Evidence map›Paper›PMID 39693194›Full record

ArticleHuman vaccines & immunotherapeutics2024

Effectiveness of the influenza vaccine for preventing laboratory-confirmed influenza infections in outpatient immunocompromised adults, 2017-2018.

Kailey Hughes Kramer, Richard K Zimmerman, Catherine L Haggerty, G K Balasubramani, Mary Patricia Nowalk, Emily T Martin, Manjusha Gaglani, C Hallie Phillips, Edward Belongia, Jessie Chung and 1 more

Abstract read
In one paragraph

Article in Human vaccines & immunotherapeutics, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Kailey Hughes KramerMedicine, Infectious Diseases, University of Pittsburgh, Pittsburgh, PA, USA.ORCID 0000-0002-7028-6062
Richard K ZimmermanMedicine, Infectious Diseases, University of Pittsburgh, Pittsburgh, PA, USA.
Catherine L HaggertyMedicine, Infectious Diseases, University of Pittsburgh, Pittsburgh, PA, USA.
G K BalasubramaniMedicine, Infectious Diseases, University of Pittsburgh, Pittsburgh, PA, USA.
Mary Patricia NowalkMedicine, Infectious Diseases, University of Pittsburgh, Pittsburgh, PA, USA.
Emily T MartinEpidemiology, University of Michigan, Ann Arbor, MI, USA.
Manjusha GaglaniPediatrics, Pediatric Infectious Diseases, Baylor Scott and White, Austin, TX, USA.
C Hallie PhillipsKaiser Permanente Washington Health Research Institute, Seattle, WA, USA.
Edward BelongiaCenter for Clin Epidemiology & Population Health, Marshfield Clinic Research Institute, Marshfield, WI, USA.
Jessie ChungInfluenza Division, Centers for Disease Control and Prevention, Atlanta, GA, USA.
Fernanda P SilveiraMedicine, Infectious Diseases, University of Pittsburgh, Pittsburgh, PA, USA.

Funding

University of Pittsburgh Clinical and Translational Science InstituteUL1TR001857 · NCATS · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI REIS, STEVEN E · 2016 to 2025
$129.3M
NCATS NIH HHS UL1 TR001857NCIRD CDC HHS U01 IP000969NCIRD CDC HHS U01 IP001039
6 · The paper itself

Abstract

While the number of immunocompromised (IC) individuals continues to rise, the existing literature on influenza vaccine effectiveness (VE) in IC populations is limited. Understanding the vaccine effectiveness (VE) of the seasonal influenza vaccines in immunocompromised (IC) populations remains paramount. Using 2017-2018 US Flu VE Network data, we examined the VE of the 2017-2018 seasonal influenza vaccine against symptomatic influenza in outpatient settings among IC adults. We used logistic regression and adjusted for enrollment site, race, self-reported general health status, age, and onset date of symptoms. The VE among non-IC was 31% (95% CI: 22, 39) and among IC participants was -4% (95% CI: -66, 35), though the difference was not statistically significant. This study demonstrates the capacity to study a large IC population using an existing influenza VE network and contributes to the literature to support large, multicenter VE studies for IC populations.

Indexed as

Immunocompromised HostInfluenza, HumanInfluenza VaccinesOutpatientsVaccine EfficacyAdolescentAdultAgedFemaleHumansMaleMiddle AgedUnited StatesVaccinationYoung AdultInfluenza VaccinesimmunocompromisedInfluenzavaccinevaccine effectiveness

Identifiers

PMID39693194
PMCPMC11188783

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.