Evidence map›Paper›PMID 39692954›Full record

ReviewClinical autonomic research : official journal of the Clinical Autonomic Research Society2025

Sphenopalatine ganglion stimulation for the treatment of cerebrovascular ischemia.

Juan Manuel Marquez-Romero, Karen Itzel Sánchez-Ramírez

Abstract readReview
PubMed Publisher
In one paragraph

Review in Clinical autonomic research : official journal of the Clinical Autonomic Research Society, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Juan Manuel Marquez-RomeroDepartment of Neurology, Hospital General de Zona #2, IMSS, OOAD Aguascalientes, Av. los Conos No. 102, 20190, Aguascalientes, AGS, Mexico. scint1st@gmail.com.ORCID http://orcid.org/0000-0002-5059-1174
Karen Itzel Sánchez-RamírezFacultad de Medicina, Universidad Autónoma de Sinaloa, C. Sauces, s/n, 80019, Culiacán, SIN, Mexico.ORCID http://orcid.org/0009-0007-2709-7489

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThe parasympathetic effects of the sphenopalatine ganglion (SPG) on the cerebral vasculature provide a compelling rationale for its therapeutic application in cerebrovascular ischemia. In recent years, attempts have been made to stimulate the SPG to achieve beneficial effects on cerebral circulation.

methodsThis review synthesizes the available publications on SPG stimulation. It critically evaluates the evidence from preclinical studies and clinical trials to assess its potential as a treatment for acute cerebrovascular disorders and outlines aspects that still require more study.

resultsThe medical literature provides consistent evidence of the significant effects of stimulating the SPG on cerebrovascular circulation. In addition, considerable evidence supports the therapeutic role of SPG stimulation in patients with cerebral ischemia.

conclusionGiven the current understanding, future research could explore the potential of SPG stimulation as a non-reperfusion intervention to improve long-term outcomes for individuals with ischemic cerebrovascular conditions.

Indexed as

Brain IschemiaElectric Stimulation TherapyGanglia, ParasympatheticAnimalsCerebrovascular CirculationHumansChemicalElectric stimulationGangliaParasympathetic nervous systemPterygopalatineStimulationStroke

Identifiers

PMID39692954

What OpenQuestion holds

Textmetadata
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.