Evidence map›Paper›PMID 39692856›Full record

ArticleChild's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery2024

Selective dorsal rhizotomy outcomes in mixed spasticity and dystonia cases.

Ahmed Aly, Mostafa Elmaghraby, Andrew Dapaah, Benjamin Hall, Christine Sneade, Benedetta Pettorini

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Article in Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

6 authors.

Ahmed AlyDepartment of Neurosurgery, Alder Hey Children's Hospital, Liverpool, L14 5AB, UK. ahmedhma88@gmail.com.ORCID 0000-0002-1389-8097
Mostafa ElmaghrabyDepartment of Neurosurgery, Alder Hey Children's Hospital, Liverpool, L14 5AB, UK. mostafa.elmaghraby@azhar.edu.eg.ORCID 0000-0002-8602-0701
Andrew Dapaah
Benjamin HallDepartment of Neurosurgery, Alder Hey Children's Hospital, Liverpool, L14 5AB, UK.
Christine SneadeDepartment of Physiotherapy, Alder Hey Children's Hospital, Liverpool, L14 5AB, UK.
Benedetta PettoriniDepartment of Neurosurgery, Alder Hey Children's Hospital, Liverpool, L14 5AB, UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionThis study investigated the effects of selective dorsal rhizotomy (SDR) on dystonia and dystonic posture in patients with cerebral palsy (CP) presenting with mixed spasticity and dystonia.

methodA prospective, single-centre study was conducted at a UK supra-regional centre from May 2013 to September 2022. All children with spasticity, dystonia and/or dystonic posture undergoing SDR were included. The primary outcome measure was pre- and postoperative assessment of dystonic posture. Dystonia severity was measured using the Barry-Albright dystonia (BAD) scale.

resultsTwo hundred and fifty-seven patients (aged 3-18 years) underwent SDR. Forty-three patients had dystonia and 52 exhibited dystonic posture without dystonia. At 3-month follow-up (n = 29), GMFCS levels tended to decrease, returning to baseline at 6 months (n = 25). Two patients required medication adjustments post-surgery. Dystonia levels remained unchanged in the dystonia group. In the dystonic posture group, 33 patients showed no change, while 21 improved.

conclusionSDR may be beneficial for carefully selected patients with dystonia or dystonic posture, without worsening these conditions. Optimal patient selection, clear communication of surgical goals and multidisciplinary involvement are crucial.

Indexed as

Cerebral PalsyDystoniaMuscle SpasticityRhizotomyAdolescentChildChild, PreschoolFemaleHumansMaleProspective StudiesTreatment OutcomeDystoniaMixedOutcomesSDRSelective dorsal rhizotomySpasticity

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.