Evidence map›Paper›PMID 39692806›Full record

ReviewDiscover oncology2024

The therapeutic use of 177 Lu-PSMA-617 radioligand therapy in prostate cancer treatment: a review of literature and ongoing trials.

Alexander Konopnicki, Michael Zaliznyak, Mathews Roy, Bagi Jana

Abstract readReview
In one paragraph

Review in Discover oncology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Pivotal Phase 3 Theranostic Trials: Future Indications.Journal of nuclear medicine : official publication, Society of Nuclear Medicine · 2026
    Review
  2. Article
  3. Article
  4. Review
  5. Review
  6. Framework to calculateMedical physics · 2025
    Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Alexander KonopnickiDepartment of Internal Medicine, University of Texas Medical Branch, Galveston, TX, USA.
Michael ZaliznyakDepartment of Urology, University of California San Francisco, San Francisco, CA, USA.
Mathews RoyDepartment of Internal Medicine, University of Texas Medical Branch, Galveston, TX, USA.
Bagi JanaDepartment of General Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, 77030, USA. brjana@utmb.edu.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Radioligand therapy is a targeted cancer treatment modality in which radioisotopes are utilized in the delivery of radiation at targeted cancer cells, with the goal of sparing normal cells. Prostate cancer is a well-known radiosensitive disease, historically treated with radioisotopes such as Strontium-89, Samarium-153, and Radium-223 for palliation of bone metastases. Recently, prostate specific membrane antigen (PSMA) has recently been employed as a radioligand target due to its unique properties of high expression on the surface of prostate cancer cells, limited expression in normal tissue, function as an internalizing cell surface receptor, and increased expression with androgen deprivation therapy. In 2015,

Indexed as

177Lu-PSMA-617Prostate CancerRadioligand therapy

Identifiers

PMID39692806
PMCPMC11655789

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.