ArticleAlzheimer's & dementia : the journal of the Alzheimer's Association2025
Individual and joint associations between sleep duration and physical activity with cognitive function: A longitudinal analysis among middle-aged and older adults in China.
Article in Alzheimer's & dementia : the journal of the Alzheimer's Association, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed.
- [Progress on prognostic assessment methods for mild cognitive impairment].Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences · 2026Review
- Correlation between thyroid hormone levels and cognitive dysfunction in older patients with subclinical hypothyroidism : A matched groups retrospective study.Wiener klinische Wochenschrift · 2026Article
- Joint association of physical function and sleep duration with incident depressive symptoms among middle-aged and older Chinese.BMC public health · 2026Observational
- Associations Between Sleep Duration and Cognitive Function Among Older Adults: Cross-Sectional Study.JMIR human factors · 2025Article
- Individual and joint associations between sleep duration and physical activity with cognitive function: a longitudinal analysis among middle-aged and older adults in China.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2025Article
- Individual and joint associations between sleep duration and physical activity with cognitive function: A longitudinal analysis among middle-aged and older adults in China.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2025Article
- Independent and joint associations of sleep quality and physical activity with glycaemic control in patients with type 2 diabetes mellitus.Frontiers in nutrition · 2025Article
- Associations between sleep duration, physical activity, and cognitive impairment in older adults-empirical analysis based on CHARLS data.Frontiers in public health · 2025Article
- Physical activity may mitigate sleep-related cognitive deficits in older adults: Findings from the IGNITE study.Alzheimer's & dementia (New York, N. Y.)Article
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Authors and funding
14 authors.
Funding
Abstract
introductionStudies using cross-sectional data or with a short follow-up period fail to distinguish whether the associations between sleep duration and physical activity with cognitive function result from reverse causation.
methodsThe longitudinal study examined the individual and joint associations, with specific temporality, between sleep duration and physical activity with cognitive function, using time-lagged linear mixed models and generalized additive mixed models.
resultsA total of 14,694 participants aged ≥ 50 years were included, with an average lagged time of 4.5 (standard deviation 1.3) years. Long sleep duration was independently associated with cognitive decline, while short sleep duration and physical activity were not. The analysis of joint effects showed that increased physical activity slowed the rate of cognitive decline among participants reporting long sleep duration, consistent with the results of the stratified analyses. DISCUSSION: Interventions on improving sleep should consider concurrent physical activity to maximize benefits for slowing cognitive decline. HIGHLIGHTS: Long sleep duration was independently associated with worse cognitive function, while short sleep duration was not. Elevated levels of physical activity were not independently associated with better cognitive function. Increased physical activity appeared to mitigate the negative impact of long sleep duration on cognitive function.
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