ArticleTechnology in cancer research & treatment
Predicting High-Grade Patterns in Stage I Solid Lung Adenocarcinoma: A Study of 371 Patients Using Refined Radiomics and Deep Learning-Guided CatBoost Classifier.
Article in Technology in cancer research & treatment. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Radiomics to understand pre-treatment tumor biology for resectable non-small cell lung cancer.Frontiers in oncology · 2026Review
- Advantages of integrating artificial intelligence and spectral CT for lung nodule classification and prognostic judgment: a narrative review.Journal of thoracic disease · 2025Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionThis study aimed to devise a diagnostic algorithm, termed the Refined Radiomics and Deep Learning Features-Guided CatBoost Classifier (RRDLC-Classifier), and evaluate its efficacy in predicting pathological high-grade patterns in patients diagnosed with clinical stage I solid lung adenocarcinoma (LADC).
methodsIn this retrospective study, a total of 371 patients diagnosed with clinical stage I solid LADC were randomly categorized into training and validation sets in a 7:3 ratio. Uni- and multivariate logistic regression analyses were performed to examine the imaging findings that can be used to predict pathological high-grade patterns meticulously. Employing redundancy and the least absolute shrinkage and selection operator regression, a radiomics model was developed. Subsequently, radiomics refinement and deep learning features were employed using a machine learning algorithm to construct the RRDLC-Classifier, which aims to predict high-grade patterns in clinical stage I solid LADC. Evaluation metrics, such as receiver operating characteristic curves, areas under the curve (AUCs), accuracy, sensitivity, and specificity, were computed for assessment.
resultsThe RRDLC-Classifier attained the highest AUC of 0.838 (95% confidence interval [CI]: 0.766-0.911) in predicting high-grade patterns in clinical stage I solid LADC, followed by radiomics with an AUC of 0.779 (95% CI: 0.675-0.883), and imaging findings with an AUC of 0.6 (95% CI: 0.472-0.726).
conclusionsThis study introduces the RRDLC-Classifier, a novel diagnostic algorithm that amalgamates refined radiomics and deep learning features to predict high-grade patterns in clinical stage I solid LADC. This algorithm may exhibit excellent diagnostic performance, which can facilitate its application in precision medicine.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.