Evidence map›Paper›PMID 39692510›Full record

ArticlemSystems2025

Valine potentiates cefoperazone-sulbactam to kill methicillin-resistant

Shao-Hua Li, Yuan Tao, Zhi-Cheng Yang, Huan-Zhe Fu, Hui-Yin Lin, Xuan-Xian Peng, Hui Li

Abstract read
In one paragraph

Article in mSystems, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Article
  2. Article
  3. CRISPR-driven strategies to disrupt methicillin-resistantFrontiers in cellular and infection microbiology · 2026
    Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Shao-Hua LiState Key Laboratory of Bio-Control, School of Life Sciences, Southern Marine Science and Engineering Guangdong Laboratory (Zhuhai), Sun Yat-sen University, Guangzhou, China.ORCID 0009-0000-1061-5445
Yuan TaoState Key Laboratory of Bio-Control, School of Life Sciences, Southern Marine Science and Engineering Guangdong Laboratory (Zhuhai), Sun Yat-sen University, Guangzhou, China.
Zhi-Cheng YangState Key Laboratory of Bio-Control, School of Life Sciences, Southern Marine Science and Engineering Guangdong Laboratory (Zhuhai), Sun Yat-sen University, Guangzhou, China.
Huan-Zhe FuState Key Laboratory of Bio-Control, School of Life Sciences, Southern Marine Science and Engineering Guangdong Laboratory (Zhuhai), Sun Yat-sen University, Guangzhou, China.
Hui-Yin LinState Key Laboratory of Bio-Control, School of Life Sciences, Southern Marine Science and Engineering Guangdong Laboratory (Zhuhai), Sun Yat-sen University, Guangzhou, China.ORCID 0000-0003-2600-4838
Xuan-Xian PengState Key Laboratory of Bio-Control, School of Life Sciences, Southern Marine Science and Engineering Guangdong Laboratory (Zhuhai), Sun Yat-sen University, Guangzhou, China.
Hui LiState Key Laboratory of Bio-Control, School of Life Sciences, Southern Marine Science and Engineering Guangdong Laboratory (Zhuhai), Sun Yat-sen University, Guangzhou, China.ORCID 0000-0003-2600-4838

Funding

MOST | National Key Research and Development Program of China (NKPs) 2023YFD1800104MOST | National Natural Science Foundation of China (NSFC) 32270199MOST | National Natural Science Foundation of China (NSFC) 42276125
6 · The paper itself

Abstract

Metabolic state-reprogramming approach was extended from Gram-negative bacteria to Gram-positive bacterium methicillin-resistant IMPORTANCE: Methicillin-resistant

Indexed as

Anti-Bacterial AgentsCefoperazoneMethicillin-Resistant Staphylococcus aureusStaphylococcal InfectionsSulbactamValineAnimalsDrug SynergismFemaleHumansMiceMicrobial Sensitivity TestsAnti-Bacterial AgentsCefoperazoneSulbactamValineantibiotic resistancecefoperazone and sulbactammetabolic reprogrammingMRSAvaline

Identifiers

PMID39692510
PMCPMC11748551

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.