Evidence map›Paper›PMID 39691601›Full record

ArticleFrontiers in oncology2024

Castleman disease variant of POEMS syndrome without M protein: a case report.

Min Ji, Shumin Jin, Shaolei Zang, Peng Li, Fei Lu, Chuanli Zhao, Chunqing Zhang, Chunyan Ji, Jingjing Ye

Abstract readCase Reports
In one paragraph

Article in Frontiers in oncology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Min Ji *Department of Hematology, Qilu Hospital, Cheeloo College of Medicine, Shandong University, Jinan, China.
Shumin Jin *Department of Hematology, Qilu Hospital, Cheeloo College of Medicine, Shandong University, Jinan, China.
Shaolei ZangDepartment of Hematology, Qilu Hospital, Cheeloo College of Medicine, Shandong University, Jinan, China.
Peng LiDepartment of Hematology, Qilu Hospital, Cheeloo College of Medicine, Shandong University, Jinan, China.
Fei LuDepartment of Hematology, Qilu Hospital, Cheeloo College of Medicine, Shandong University, Jinan, China.
Chuanli ZhaoDepartment of Hematology, Qilu Hospital, Cheeloo College of Medicine, Shandong University, Jinan, China.
Chunqing ZhangDepartment of Hematology, Qilu Hospital, Cheeloo College of Medicine, Shandong University, Jinan, China.
Chunyan JiDepartment of Hematology, Qilu Hospital, Cheeloo College of Medicine, Shandong University, Jinan, China.
Jingjing YeDepartment of Hematology, Qilu Hospital, Cheeloo College of Medicine, Shandong University, Jinan, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

POEMS (polyneuropathy, organomegaly, endocrinopathy, monoclonal protein, skin changes) syndrome is a paraneoplastic syndrome associated with an underlying plasma cell neoplasm. According to the current diagnostic criteria for POEMS syndrome, the presence of characteristic polyneuropathy and clonal plasma cell disorder are required for diagnosis. We report a case of a Castleman disease variant of POEMS syndrome without monoclonal protein (M protein) expression, which presented with polyneuropathy, organomegaly, endocrinopathy, skin lesions, and sclerotic bone lesions. The patient was treated with lenalidomide and dexamethasone (RD), after which her symptoms improved. The findings in this case suggest that the diagnostic criteria for POEMS syndrome might require reconsideration.

Indexed as

case reportCastleman diseasediagnostic criteriamonoclonal proteinPOEMS syndrome

Identifiers

PMID39691601
PMCPMC11649650

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.