MT-SCnet: multi-scale token divided and spatial-channel fusion transformer network for microscopic hyperspectral image segmentation.

Introduction: Hybrid architectures based on convolutional neural networks and Transformers, effectively captures both the local details and the overall structural context of lesion tissues and cells, achieving highly competitive segmentation results in microscopic hyperspectral image (MHSI) segmentation tasks. However, the fixed tokenization schemes and single-dimensional feature extraction and fusion in existing methods lead to insufficient global feature extraction in hyperspectral pathology images. Methods: Base on this, we propose a multi-scale token divided and spatial-channel fusion transformer network (MT-SCnet) for MHSIs segmentation. Specifically, we first designed a Multi-Scale Token Divided module. It divides token at different scale based on mirror padding and promotes information interaction and fusion between different tokens to obtain more representative features for subsequent global feature extraction. Secondly, a novel spatial channel fusion transformer was designed to capture richer features from spatial and channel dimensions, and eliminates the semantic gap between features from different dimensions based on cross-attention fusion block. Additionally, to better restore spatial information, deformable convolutions were introduced in decoder. Results: The Experiments on two MHSI datasets demonstrate that MT-SCnet outperforms the comparison methods. Discussion: This advance has significant implications for the field of MHSIs segmentation. Our code is freely available at https://github.com/sharycao/MT-SCnet.