ArticleNeurophotonics2024
Effects of red blood cell transfusion on cerebral hemodynamics of preterm neonates.
Article in Neurophotonics, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed.
- "hDOS": an automated hybrid diffuse optical device for real-time noninvasive tissue monitoring: precision andJournal of biomedical optics · 2025Article
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13 authors.
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No grant is acknowledged in the PubMed record.
Abstract
Significance: Anemia is a common problem in preterm neonates, and red blood cell transfusion (RBCT) is used to improve oxygen delivery. However, RBCT is associated with complications, although an increase in cerebral oxygenation has been documented, and no universally accepted biomarker for the need for transfusion (i.e., the concentration of hemoglobin in the blood) has been defined. Aim: We used a hybrid optical device (BabyLux device) that merges time-domain near-infrared spectroscopy (TD-NIRS) and diffuse correlation spectroscopy (DCS) to potentially obtain a better assessment of the cerebral effects of RBCT compared with previous studies using continuous wave (CW) spatially resolved NIRS. Approach: Eighteen clinically stable preterm neonates were assessed before and after RBCT by the BabyLux device as five repetitions of 60 s measurement (with 1 s acquisition time), estimating the cerebral blood flow (CBF) as a blood flow index (BFI), the total hemoglobin concentration (tHb), and the cerebral tissue oxygen saturation ( Results: The BabyLux data from four neonates did not meet quality criteria and were discarded. After the transfusion, tHb and Conclusions: The results confirm previous CW-NIRS studies, but the wide variability of BFI makes the effects of RBCT on cerebral metabolism uncertain.
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