Evidence map›Paper›PMID 39691472›Full record

ArticleIEEE open journal of engineering in medicine and biology2024

Complex Hemodynamic Responses to Trans-Vascular Electrical Stimulation of the Renal Nerve in Anesthetized Pigs.

Filippo Agnesi, Lucia Carlucci, Gia Burjanadze, Fabio Bernini, Khatia Gabisonia, John W Osborn, Silvestro Micera, Fabio A Recchia

Abstract read
In one paragraph

Article in IEEE open journal of engineering in medicine and biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Filippo AgnesiInterdisciplinary Research Center "Health Science"Scuola Superiore Sant'Anna Pisa 56127 Italy.ORCID https://orcid.org/0000-0003-1780-8084
Lucia CarlucciInterdisciplinary Research Center "Health Science"Scuola Superiore Sant'Anna Pisa 56127 Italy.
Gia BurjanadzeInterdisciplinary Research Center "Health Science"Scuola Superiore Sant'Anna Pisa 56127 Italy.ORCID https://orcid.org/0009-0003-7953-6878
Fabio BerniniInterdisciplinary Research Center "Health Science"Scuola Superiore Sant'Anna Pisa 56127 Italy.
Khatia GabisoniaInterdisciplinary Research Center "Health Science"Scuola Superiore Sant'Anna Pisa 56127 Italy.
John W OsbornDepartment of Integrative Biology and Physiology, Medical SchoolUniversity of Minnesota Minneapolis MN 55455 USA.ORCID https://orcid.org/0000-0002-8109-1578
Silvestro MiceraThe BioRobotics Institute, Department of Excellence in Robotics & AIScuola Superiore Sant'Anna Pisa 56127 Italy.ORCID https://orcid.org/0000-0003-4396-8217
Fabio A RecchiaScuola Superiore Sant'Anna Pisa 56127 Italy.ORCID https://orcid.org/0000-0002-4189-8465

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The objective of this study was to characterize hemodynamic changes during trans-vascular stimulation of the renal nerve and their dependence on stimulation parameters. We employed a stimulation catheter inserted in the right renal artery under fluoroscopic guidance, in pigs. Systolic, diastolic and pulse blood pressure and heart rate were recorded during stimulations delivered at different intravascular sites along the renal artery or while varying stimulation parameters (amplitude, frequency, and pulse width). Blood pressure changes during stimulation displayed a pattern more complex than previously described in literature, with a series of negative and positive peaks over the first two minutes, followed by a steady state elevation during the remainder of the stimulation. Pulse pressure and heart rate only showed transient responses, then they returned to baseline values despite constant stimulation. The amplitude of the evoked hemodynamic response was roughly linearly correlated with stimulation amplitude, frequency, and pulse width.

Indexed as

Electrical stimulationrenal nervetrans-vascular stimulation

Identifiers

PMID39691472
PMCPMC11651661

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.