Evidence map›Paper›PMID 39691286›Full record

ArticleOpen forum infectious diseases2024

Risk Factors for Spotted Fever Group Rickettsioses in Kilimanjaro Region, Tanzania.

Thomas R Bowhay, Matthew P Rubach, Ângelo J F Mendes, William L Nicholson, Jamie L Perniciaro, Michael J Maze, Ganga S Moorthy, Jo E B Halliday, Kathryn J Allan, Blandina T Mmbaga and 7 more

Abstract read
In one paragraph

Article in Open forum infectious diseases, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Thomas R BowhayCentre for International Health, University of Otago, Dunedin, New Zealand.ORCID https://orcid.org/0000-0001-9148-4837
Matthew P RubachDivision of Infectious Diseases and International Health, Department of Medicine, Duke University Medical Center, Durham, North Carolina, USA.ORCID https://orcid.org/0000-0001-5262-1421
Ângelo J F MendesSchool of Biodiversity, One Health and Veterinary Medicine, College of Medical Veterinary and Life Sciences, University of Glasgow, Glasgow, United Kingdom.ORCID https://orcid.org/0000-0003-1996-7134
William L NicholsonRickettsial Zoonoses Branch, Division of Vector-Borne Diseases, National Center for Emerging and Zoonotic Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia, USA.
Jamie L PerniciaroRickettsial Zoonoses Branch, Division of Vector-Borne Diseases, National Center for Emerging and Zoonotic Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia, USA.
Michael J MazeDepartment of Medicine, University of Otago, Christchurch, New Zealand.ORCID https://orcid.org/0000-0001-8909-1508
Ganga S MoorthyDuke Global Health Institute, Duke University, Durham, North Carolina, USA.ORCID https://orcid.org/0000-0003-3191-1117
Jo E B HallidaySchool of Biodiversity, One Health and Veterinary Medicine, College of Medical Veterinary and Life Sciences, University of Glasgow, Glasgow, United Kingdom.ORCID https://orcid.org/0000-0002-1329-9035
Kathryn J AllanSchool of Biodiversity, One Health and Veterinary Medicine, College of Medical Veterinary and Life Sciences, University of Glasgow, Glasgow, United Kingdom.ORCID https://orcid.org/0000-0001-6612-889X
Blandina T MmbagaDepartment of Medicine, Kilimanjaro Christian Medical Centre, Moshi, Tanzania.ORCID https://orcid.org/0000-0002-5550-1916
Wilbrod SagandaDepartment of Medicine, Mawenzi Regional Referral Hospital, Moshi, Tanzania.
Bingileki F LwezaulaDepartment of Medicine, Mawenzi Regional Referral Hospital, Moshi, Tanzania.ORCID https://orcid.org/0000-0003-2909-9705
Rudovick R KazwalaDepartment of Veterinary Medicine and Public Health, Sokoine University of Agriculture, Morogoro, Tanzania.ORCID https://orcid.org/0000-0003-3918-1323
Sarah CleavelandSchool of Biodiversity, One Health and Veterinary Medicine, College of Medical Veterinary and Life Sciences, University of Glasgow, Glasgow, United Kingdom.ORCID https://orcid.org/0000-0002-0456-0959
Katrina J SharplesDepartment of Mathematics and Statistics, Division of Sciences, University of Otago, Dunedin, New Zealand.ORCID https://orcid.org/0000-0003-3821-789X
Venance P MaroDepartment of Medicine, Kilimanjaro Christian Medical Centre, Moshi, Tanzania.
John A CrumpCentre for International Health, University of Otago, Dunedin, New Zealand.ORCID https://orcid.org/0000-0002-4529-102X

Funding

University of California Global Health Institute Program for Fellows and ScholarsR25TW009343 · FIC · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI COHEN, CRAIG R, STRATHDEE, STEFFANIE A. · 2012 to 2017
$6.4M
Vanderbilt-Emory-Cornell-Duke Consortium for Global Health Fellows (VECDor)R25TW009337 · FIC · VANDERBILT UNIVERSITY MEDICAL CENTER · PI HEIMBURGER, DOUGLAS CORBETT, VERMUND, STEN H. · 2012 to 2016
$6.3M
International Clinical Trials UnitU01AI062563 · NIAID · DUKE UNIVERSITY · PI BARTLETT, JOHN A · 2004 to 2007
$4.0M
Investigating Febrile Deaths in Tanzania (INDITe)R01AI121378 · NIAID · DUKE UNIVERSITY · PI RUBACH, MATTHEW P · 2016 to 2020
$2.7M
The Impact and Society Ecology of Bacterial Zoonoses in Northern Tanzania: UnderR01TW009237 · FIC · DUKE UNIVERSITY · PI CRUMP, JOHN ANDREW · 2011 to 2014
$1.7M
Biotechnology and Biological Sciences Research Council BB/L018845/1Biotechnology and Biological Sciences Research Council BB/L018926/1FIC NIH HHS R01 TW009237FIC NIH HHS R25 TW009337FIC NIH HHS R25 TW009343NIAID NIH HHS R01 AI121378NIAID NIH HHS U01 AI062563
6 · The paper itself

Abstract

Background: Knowledge gaps exist on risk factors for spotted fever group rickettsioses (SFGR) in sub-Saharan Africa. We sought to identify SFGR risk factors in Kilimanjaro Region, Tanzania. Methods: We recruited febrile patients presenting at 2 hospitals in Moshi from February 2012 through May 2014. Standardized clinical and risk factor questionnaires were administered. SFGR exposure was defined as a Results: Of 1190 participants providing ≥1 serum sample, the median age was 21.8 (range, 0.3-100.2) years, 646 (54.3%) were female, and 650 (54.6%) had SFGR exposure. Of 731 participants with paired sera, 67 (9.2%) had acute SFGR. On multivariable analysis, odds of acute SFGR were higher in the age group 0-2 years (adjusted odds ratios [aORs] for older age groups, <0.36; Conclusions: Those aged <2 years, rural residents, and persons residing in areas with cooler temperatures had increased odds of SFGR. Our results identify groups for further research on tick exposure and for targeted prevention interventions.

Identifiers

PMID39691286
PMCPMC11651152

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.