Evidence map›Paper›PMID 39691270›Full record

ArticleEJHaem2024

Extramedullary disease in Waldenström macroglobulinemia: A population-based observational study.

Simon Østergaard, Lars Munksgaard, Torsten Holm Nielsen, Troels Hammer, Lars Møller Pedersen, Mette Ølgod Pedersen, Lise Mette Rahbek Gjerdrum

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in EJHaem, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Simon ØstergaardDepartment of Pathology Zealand University Hospital Roskilde Denmark.ORCID https://orcid.org/0009-0003-3845-1878
Lars MunksgaardDepartment of Clinical Medicine University of Copenhagen Copenhagen Denmark.
Torsten Holm NielsenDepartment of Hematology Zealand University Hospital Roskilde Denmark.
Troels HammerDepartment of Hematology Copenhagen University Hospital - Rigshospitalet Copenhagen Denmark.
Lars Møller PedersenDepartment of Clinical Medicine University of Copenhagen Copenhagen Denmark.ORCID https://orcid.org/0000-0002-9419-8841
Mette Ølgod PedersenDepartment of Pathology Zealand University Hospital Roskilde Denmark.
Lise Mette Rahbek GjerdrumDepartment of Pathology Zealand University Hospital Roskilde Denmark.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionExtramedullary disease (EMD) is a rare manifestation of Waldenström macroglobulinemia (WM), and its clinical and prognostic implications are poorly understood.

methodsIn this single-center study, we investigated the clinical significance of EMD in a cohort of 469 WM patients.

resultsEMD was identified in 30 (6.4%) patients, with the central nervous system, kidneys, and lungs being the most frequently affected sites. The cumulative incidence of EMD was 12.6% at 15 years. Median overall survival rates at 5 and 10 years for patients with EMD were 63% and 37%, respectively.

conclusionOur findings indicate a persistent risk of EMD throughout the disease course, with no significant impact on long-term survival.

Indexed as

extramedullaryextranodallymphoplasmacytic lymphomaprognosisWaldenström macroglobulinemia

Identifiers

PMID39691270
PMCPMC11647728

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.