Evidence map›Paper›PMID 39691151›Full record

ArticleCureus2024

A Comparative Effect of Different Herbal Products on Lipid Metabolism and Hepatic Tissue: An Experimental Study on a Rat Model.

Saman H Mohammed, Jamal K Shakor, Mohsin Salih, Kaniaw Khafar, Halgord M Ali, Hardi R Baqi, Dyar H Karim, Shagul J Muhammd, Chrakhan J Khdhir, Chro Raouf

Abstract read
In one paragraph

Article in Cureus, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Saman H MohammedNursing, Darbandikhan Technical Institute, Sulaimani Polytechnic University, Sulaymaniyah, IRQ.
Jamal K ShakorNursing, Darbandikhan Technical Institute, Sulaimani Polytechnic University, Sulaymaniyah, IRQ.
Mohsin SalihNursing, College of Health and Medical Technology, Sulaimani Polytechnic University, Sulaymaniyah, IRQ.
Kaniaw KhafarNursing, Technical College of Applied Sciences, Sulaimani Polytechnic University, Sulaymaniyah, IRQ.
Halgord M AliNursing, Technical College of Applied Sciences, Halabja Research Center, Sulaimani Polytechnic University, Sulaymaniyah, IRQ.
Hardi R BaqiMedical Laboratory Technology, Shaqlawa Technical College, Erbil Polytechnic University, Erbil, IRQ.
Dyar H KarimBiology, College of Science, University of Sulaimani, Sulaymaniyah, IRQ.
Shagul J MuhammdAnimal Science, College of Agricultural Engineering Sciences, University of Sulaimani, Sulaymaniyah, IRQ.
Chrakhan J KhdhirCollege of Nursing, University of Human Development, Sulaymaniyah, IRQ.
Chro RaoufMedical Laboratory of Science, College of Health Sciences, University of Human Development, Kurdistan Regional Government, Sulaymaniyah, IRQ.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background Dysregulation of lipid metabolism can lead to conditions such as hyperlipidemia, obesity, cardiovascular diseases, and hepatic steatosis. A high-fat diet (HFD) results in dysregulation of lipid metabolism and may primarily convert liver tissue to develop inflammation and fibrosis. Slimming pills, Japanese powder tea, and Shahana tea are common green teas that commercials have used for hyperlipidemia, obesity, and liver protection. The aim of this study was to investigate the effect of these three teas on dyslipidemia and liver in a rat model. Method This is an experimental study carried out on 20 adult male albino rats of about 240 g and 12 weeks old. The rats were randomly divided into five groups: Group 1: fed the standard pellet diet for four weeks; Group 2: fed with the HFD for four weeks; Group 3: fed with the HFD for the first four weeks and received Shahana tea (1.5  g/kg body weight (BW)); Group 4: fed with the HFD for the first four weeks and received Japanese powder tea (1.5  g/kg BW); and Group 5: fed with the HFD for the first four weeks and received slimming pill (0.6  g/kg BW). Blood samples were collected to measure the lipid profile in the rats. The rats were scarified under anesthesia, and liver tissue was collected for histopathological testing. Result HFD could significantly induce dyslipidemia and liver pathological disorders in model rats. Slimming pills could significantly improve total cholesterol (TC), triglycerides (TG), high-density lipoprotein (HDL), and low-density lipoprotein (LDL) compared to Japanese powder tea and Shahana tea. In comparison to the Shahana tea, Japanese powder tea had a significant outcome on LDL but not on other lipid profiles. Slimming pills and Shahana tea could preserve the normal histological features of the liver. The central vein (CV) and sinusoidal (SN) Kupffer cells significantly remained normal compared to model rats. Conclusion Slimming pills and Shahana tea have significant positive effects on lipid metabolism regulation, dyslipidemia, and preserving the liver from injury and fat accumulation. The effects of the two products are mostly concerned with their main components, such as L-carnitine and

Indexed as

dyslipidemiajapanese powder tealipid profileliver abnormalitiesshahana teaslimming pill

Identifiers

PMID39691151
PMCPMC11650103

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.