Evidence map›Paper›PMID 39691113›Full record

ArticleCureus2024

Cortical Hand Knob Stroke: A Case Report of Isolated Hand Weakness and Recovery.

Sharafath Hussain Zahir Hussain, Maria Elizabeth Vincent, Emil Tom John, Fatima Ihsan

Abstract readCase Reports
In one paragraph

Article in Cureus, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Sharafath Hussain Zahir HussainInternal Medicine, Milton Keynes University Hospital, Milton Keynes, GBR.
Maria Elizabeth VincentInternal Medicine, Milton Keynes University Hospital, Milton Keynes, GBR.
Emil Tom JohnInternal Medicine, Milton Keynes University Hospital, Milton Keynes, GBR.
Fatima IhsanInternal Medicine, Milton Keynes University Hospital, Milton Keynes, GBR.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cortical hand knob stroke is a rare form of stroke that affects the motor cortex responsible for controlling fine hand movements. This condition, most commonly caused by ischemia in the "hand knob" region of the precentral gyrus, can present with isolated hand weakness, often mimicking peripheral neuropathies and leading to diagnostic delays. We report a case of a 65-year-old right-handed woman who experienced a sudden onset of left-hand weakness, along with resolving slurred speech and facial droop, while she was working at her office. Due to her persistent left-hand weakness, magnetic resonance imaging of the brain was performed. This revealed a focal ischemic lesion in the right precentral gyrus, specifically involving the cortical hand knob region. The patient was treated with antiplatelet therapy, high-dose statins, and lifestyle modifications, including smoking cessation. Over five months, she showed significant recovery of hand strength. This case highlights the diagnostic challenge posed by cortical hand knob stroke, which is often misinterpreted as peripheral neuropathy, leading to delays in appropriate treatment. Recognizing this rare stroke subtype is essential for timely management and improved patient outcomes.

Indexed as

cerebrovascular accident (stroke)cortical handcortical hand knob strokegeneral internal medicineperipheral neuropathystrokesudden weakness

Identifiers

PMID39691113
PMCPMC11650755

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.