Evidence map›Paper›PMID 39690863›Full record

ArticleBrain and behavior2024

Investigating Task-Free Functional Connectivity Patterns in Newborns Using Functional Near-Infrared Spectroscopy.

Homa Vahidi, Alexandra Kowalczyk, Kevin Stubbs, Melab Musabi, Sriya Roychaudhuri, Michaela Kent, Soume Bhattacharya, Sandrine de Ribaupierre, Keith St Lawrence, Yalda Mohsenzadeh and 1 more

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Article in Brain and behavior, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

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5 · Who and what money

Authors and funding

11 authors.

Homa VahidiDepartment of Neuroscience, Schulich School of Medicine and Dentistry, Western University, London, Ontario, Canada.ORCID 0000-0001-6718-1537
Alexandra KowalczykDivision of Neonatal-Perinatal Medicine, Department of Pediatrics, London Health Sciences Centre, London, Ontario, Canada.
Kevin StubbsBrain and Mind Centre, Western University, London, Ontario, Canada.
Melab MusabiDivision of Neonatal-Perinatal Medicine, Department of Pediatrics, London Health Sciences Centre, London, Ontario, Canada.
Sriya RoychaudhuriDivision of Neonatal-Perinatal Medicine, Department of Pediatrics, London Health Sciences Centre, London, Ontario, Canada.
Michaela KentDepartment of Neuroscience, Schulich School of Medicine and Dentistry, Western University, London, Ontario, Canada.
Soume BhattacharyaDivision of Neonatal-Perinatal Medicine, Department of Pediatrics, London Health Sciences Centre, London, Ontario, Canada.
Sandrine de RibaupierreDepartment of Clinical Neurological Sciences, Schulich School of Medicine and Dentistry, Western University, London, Ontario, Canada.
Keith St LawrenceDepartment of Medical Biophysics, Western University, London, Ontario, Canada.
Yalda MohsenzadehBrain and Mind Centre, Western University, London, Ontario, Canada.
Emma G DuerdenBrain and Mind Centre, Western University, London, Ontario, Canada.ORCID 0000-0002-9734-7865

Funding

Brain CanadaCanadian Institutes of Health Research (CIHR)Natural Sciences and Engineering Council (NSERC)New Frontiers in Research Fund (NFRF)
6 · The paper itself

Abstract

backgroundResting-state networks (RSNs), particularly the sensorimotor network, begin to strengthe in the third trimester of pregnancy and mature extensively by term age. The integrity and structure of these networks have been repeatedly linked to neurological health outcomes in neonates, highlighting the importance of understanding the normative variations in RSNs in healthy development. Specifically, robust bilateral functional connectivity in the sensorimotor RSN has been linked to optimal neurodevelopmental outcomes in neonates.

aimIn the current study, we aimed to map the developmental trajectory of the sensorimotor RSN in awake neonates using functional near-infrared spectroscopy (fNIRS). MATERIALS &

methodsWe acquired fNIRS resting-state data from 41 healthy newborns (17 females, gestational age ranging from 36 + 0 to 42 + 1 weeks) within the first week after birth. We performed both single channel and hemispheric analyses to investigate the relationship between functional connectivity and both gestational and postnatal age.

resultsWe observed robust positive connectivity in numerous channel-pairs across the sensorimotor network, especially in the left hemisphere. Next, we examined the relationship between functional connectivity, gestational age, and postnatal age, while controlling for sex and subject effects. We found both gestational and postnatal age to be significantly associated with changes in functional connectivity in the sensorimotor RSN. In our hemispheric analysis (N DISCUSSION AND

conclusionIn summary, our findings demonstrate the utility of fNIRS for monitoring early developmental changes in functional networks in awake newborns.

Indexed as

Spectroscopy, Near-InfraredFemaleGestational AgeHumansInfant, NewbornMaleNerve NetSensorimotor CortexconnectivitydevelopmentfNIRSnewborn

Identifiers

PMID39690863
PMCPMC11652786

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.