Evidence map›Paper›PMID 39690769›Full record

ArticleBeijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences2024

[Effect of balloon occlusion combined with intra-sac injection of thrombin in the treatment of ruptured abdominal aortic aneurysm].

Shilu Zhao, Jingyuan Luan, Qichen Feng, Qijia Liu, Guangxin Yang, Zichang Jia, Jinman Zhuang

Abstract readEnglish Abstract
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Article in Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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5 · Who and what money

Authors and funding

7 authors.

Shilu ZhaoDepartment of Interventional Radiology and Vascular Surgery, Peking University Third Hospital, Beijing 100191, China.
Jingyuan LuanDepartment of Interventional Radiology and Vascular Surgery, Peking University Third Hospital, Beijing 100191, China.
Qichen FengDepartment of Interventional Radiology and Vascular Surgery, Peking University Third Hospital, Beijing 100191, China.
Qijia LiuDepartment of Interventional Radiology and Vascular Surgery, Peking University Third Hospital, Beijing 100191, China.
Guangxin YangDepartment of Interventional Radiology and Vascular Surgery, Peking University Third Hospital, Beijing 100191, China.
Zichang JiaDepartment of Interventional Radiology and Vascular Surgery, Peking University Third Hospital, Beijing 100191, China.
Jinman ZhuangDepartment of Interventional Radiology and Vascular Surgery, Peking University Third Hospital, Beijing 100191, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo investigate the safety and effectiveness of balloon occlusion and intra-sac thrombin injection in the endovascular repair of ruptured abdominal aortic aneurysm.

methodsFrom October 2019 to October 2022, the clinical data of 16 patients with rAAA treated with balloon occlusion technique and intra-sac thrombin injection combined with EVAR were retrospectively analyzed, including 13 males and 3 females, aged 42-85 years, with a median age of 70.5 years. The time of preoperative first aid (from hospital arrival to operation start), average operation time, stay in intensive care unit (ICU), average hospitalization time, success rate of surgical treatment, perioperative (30 d) mortality rate, incidence of complications, the maximum diameter and volume change of the aneurysm were observed and recorded.

resultsAmong the 16 patients with ruptured abdominal aortic aneurysm, the technical success rate was 100.0% (16/16). One patient died of multiple organ dysfunction 6 hours after operation. The success rate of surgical treatment was 93.8% (15/16). The preoperative first aid time was (53.3±6.2) min, the average operation time was (89.9±17.1) min, the stay in the intensive care unit (ICU) was (1.7±0.8) d, and the average hospitalization time was (7.8±1.3) d. The intraoperative balloon occlusion time was (32.4±4.1) min. The postoperative renal function of all the patients had no significant deterioration compared with that preoperative. Abdominal compartment syndrome (ACS) occurred in 1 patient after operation, which improved after CT puncture and drainage. The median follow-up time was 36 months. During the follow-up period, 1 patient died of acute myocardial infarction 2 years after operation, and the remaining 14 patients survived. Among the 14 follow-up patients, 1 type Ⅱ endoleak occurred, and no other types of endoleak occurred. By the end of the follow-up, the maximum diameter of the aneurysm sac in 14 patients was significantly lower than that before operation [(44.6±8.0) mm

conclusionBalloon occlusion during endovascular repair is safe and effective in the treatment of ruptured abdominal aortic aneurysm; intraoperative thrombin injection of the aneurysm sac can significantly reduce the incidence of intraoperative and postoperative abdominal compartment syndrome and endoleak and, to a certain extent, improve the success rate of treatment.

Indexed as

Aortic Aneurysm, AbdominalAortic RuptureBalloon OcclusionEndovascular ProceduresThrombinAdultAgedAged, 80 and overFemaleHumansMaleMiddle AgedOperative TimeRetrospective StudiesTreatment OutcomeThrombinBalloon occlusionEndovascular repairRuptured abdominal aortic aneurysmThrombin

Identifiers

PMID39690769
PMCPMC11652995

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.