Evidence map›Paper›PMID 39690446›Full record

ArticleCirculation research2025

SGLT2 Inhibition Induces Cardioprotection by Increasing Parasympathetic Activity.

Maryna V Basalay, Alla Korsak, Zhenhe He, Alexander V Gourine, Sean M Davidson, Derek M Yellon

Abstract readLetter
PubMed Full text at PMC Publisher
In one paragraph

Article in Circulation research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Brain and hypertension: from sympathetic outflow to brain-focused blood pressure management.Hypertension research : official journal of the Japanese Society of Hypertension · 2026
    Review
  2. Vascular (dys)function in the failing heart.Nature reviews. Cardiology · 2025
    Review
  3. Review
  4. Article
  5. Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Maryna V Basalay *The Hatter Cardiovascular Institute, University College London, United Kingdom (M.V.B., Z.H., S.M.D., D.M.Y.).ORCID 0000-0001-5608-3878
Alla Korsak *Department of Neuroscience, Physiology and Pharmacology, Centre for Cardiovascular and Metabolic Neuroscience, University College London, United Kingdom (A.K., A.V.G.).
Zhenhe HeThe Hatter Cardiovascular Institute, University College London, United Kingdom (M.V.B., Z.H., S.M.D., D.M.Y.).ORCID 0000-0002-8513-0351
Alexander V GourineDepartment of Neuroscience, Physiology and Pharmacology, Centre for Cardiovascular and Metabolic Neuroscience, University College London, United Kingdom (A.K., A.V.G.).
Sean M DavidsonThe Hatter Cardiovascular Institute, University College London, United Kingdom (M.V.B., Z.H., S.M.D., D.M.Y.).ORCID 0000-0001-5182-4980
Derek M YellonThe Hatter Cardiovascular Institute, University College London, United Kingdom (M.V.B., Z.H., S.M.D., D.M.Y.).ORCID 0000-0001-7791-9320

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

glucoseheart failuremyocardial infarctionsodium-glucose transporter 2sodium-glucose transporter 2 inhibitorsvagus nerve

Identifiers

PMID39690446
PMCPMC11741129

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.