Evidence map›Paper›PMID 39690313›Full record

ArticleAnalytical and bioanalytical chemistry2025

Updates implemented in version 4 of the GlyCosmos Glycoscience Portal.

Sunmyoung Lee, Tamiko Ono, Shiota Masaaki, Akihiro Fujita, Masaaki Matsubara, Achille Zappa, Issaku Yamada, Kiyoko F Aoki-Kinoshita

Abstract read
In one paragraph

Article in Analytical and bioanalytical chemistry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Sunmyoung LeeGlycan and Life Systems Integration Center (GaLSIC), Soka University, Hachioji, Tokyo, Japan.
Tamiko OnoGlycan and Life Systems Integration Center (GaLSIC), Soka University, Hachioji, Tokyo, Japan.
Shiota MasaakiGlycan and Life Systems Integration Center (GaLSIC), Soka University, Hachioji, Tokyo, Japan.
Akihiro FujitaInstitute for Glyco-Core Research, Nagoya University, Nagoya, Japan.
Masaaki MatsubaraThe Noguchi Institute, Tokyo, Japan.
Achille ZappaGlycan and Life Systems Integration Center (GaLSIC), Soka University, Hachioji, Tokyo, Japan.
Issaku YamadaThe Noguchi Institute, Tokyo, Japan.
Kiyoko F Aoki-KinoshitaGlycan and Life Systems Integration Center (GaLSIC), Soka University, Hachioji, Tokyo, Japan. kkiyoko@soka.ac.jp.

Funding

Japan Science and Technology (JST) - National Bioscience Database Center (NBDC) JPMJND2204
6 · The paper itself

Abstract

Glycosylation, characterized by its complexity and diversity, is a common system across all domains of life. The glycosylation of proteins or lipids imparts them with structural and functional roles, ranging from development to infectious or Mendelian disease. The high-throughput-based omics data has revealed that glycans are involved in important cellular processes. Comprehensive knowledge of glycosylation has contributed not only to the fundamental concepts in glycoscience but also to its applications, including the development of molecular markers for diagnosis and therapeutic tools for treating diseases. The GlyCosmos Glycoscience Portal (GlyCosmos) has undergone significant updates to better support the scientific community in studying glycosylation-related phenomena. Key enhancements include the integration of expanded datasets linking glycans to other omics fields, improved tools for glycan structure prediction and analysis, and upgraded visualization capabilities to streamline data interpretation. A strengthened focus on data standardization has also been introduced, fostering interoperability between glycoscience resources and external databases. Since its release in 2019, the portal has seen a fivefold increase in user engagement, reflecting its growing relevance. These recent advancements aim to provide researchers with a more comprehensive and user-friendly platform, enabling deeper insights into glycan roles in cellular processes and disease mechanisms. GlyCosmos will continue to evolve, prioritizing community needs and advancing the integration of glycoscience with broader biological and biomedical research.

Indexed as

Databases, FactualGlycomicsPolysaccharidesGlycosylationHumansPolysaccharidesData integrationGlycan-related diseaseGlycan-related genesGlycansRepository

Identifiers

PMID39690313
PMCPMC11782317

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.