Evidence map›Paper›PMID 39690312›Full record

ArticleGraefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie2025

Effects of ambient atmospheric pressure on intraocular pressure measured using a Goldman applanation tonometer in normal eyes under ordinary conditions.

Toru Ikushima, Aiko Iwase, Makoto Araie, Hiroshi Murata, Morio Ueno, Kazuhiko Mori, Yoko Ikeda, Hiroki Mieno, Chie Sotozono, Shigeru Kinoshita and 1 more

Abstract readMulticenter Study
In one paragraph

Article in Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Effects of relative humidity on intraocular pressure using a time-series analysis.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2026
    Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Toru IkushimaDepartment of Ophthalmology, Kyoto Prefectural University of Medicine, 465 Kajii-cho, Kawaramachi-Hirokoji, Kamigyo-ku, Kyoto, 602-0841, Japan. itoru0827@gmail.com.ORCID http://orcid.org/0009-0000-6448-5762
Aiko IwaseTajimi Iwase Eye Clinic, Tajimi, Gifu, Japan.
Makoto AraieKanto Central Hospital of the Mutual Aid Association of Public School Teachers, Tokyo, Japan.
Hiroshi MurataCenter Hospital of the National Center for Global Health and Medicine, Tokyo, Japan.
Morio UenoDepartment of Ophthalmology, Kyoto Prefectural University of Medicine, 465 Kajii-cho, Kawaramachi-Hirokoji, Kamigyo-ku, Kyoto, 602-0841, Japan.
Kazuhiko MoriDepartment of Ophthalmology, Kyoto Prefectural University of Medicine, 465 Kajii-cho, Kawaramachi-Hirokoji, Kamigyo-ku, Kyoto, 602-0841, Japan.
Yoko IkedaDepartment of Ophthalmology, Kyoto Prefectural University of Medicine, 465 Kajii-cho, Kawaramachi-Hirokoji, Kamigyo-ku, Kyoto, 602-0841, Japan.
Hiroki MienoDepartment of Ophthalmology, Kyoto Prefectural University of Medicine, 465 Kajii-cho, Kawaramachi-Hirokoji, Kamigyo-ku, Kyoto, 602-0841, Japan.
Chie SotozonoDepartment of Ophthalmology, Kyoto Prefectural University of Medicine, 465 Kajii-cho, Kawaramachi-Hirokoji, Kamigyo-ku, Kyoto, 602-0841, Japan.
Shigeru KinoshitaDepartment of Frontier Medical Science and Technology for Ophthalmology, Kyoto Prefectural University of Medicine, Kyoto, Japan.
Tetsuya YamamotoKaiya Eye Clinic, Hamamatsu, Shizuoka, Japan.

Funding

Japan Glaucoma Society Data Center Budget Japan Glaucoma Society Data Center Budget
6 · The paper itself

Abstract

purposeLittle is known about the effects of ambient atmospheric pressure (AP) on intraocular pressure (IOP) under ordinary conditions. This study aimed to investigate the effects of AP on Goldmann applanation tonometer-measured IOP (GAT-IOP) in normal eyes under everyday atmospheric conditions adjusting for effects of possible confounding factors including other climatic factors.

methodsData obtained from 2,431 normal healthy eyes of 2,431 subjects (mean age: 56.9 years) who participated in this population-based glaucoma survey in Japan were analyzed via multivariable linear regression analysis, where the GAT-IOP was the response variable; explanatory variables were the ocular and systemic factors and calendar factors reportedly correlated with GAT-IOP as well as AP, relative humidity, temperature, wind speed, and weather. The Bonferroni correction was adopted to obtain P values.

resultsOnly AP of the outside air when each subject was examined was positively correlated with GAT-IOP (regression coefficient (RC) = 0.0460; P = 0.0051). Central corneal thickness, body mass index, and systolic blood pressure were positively correlated (RC = 0.0133, 0.0754, 0.0131; P < 0.0001, P < 0.0001, P = 0.0016, respectively), and corneal curvature radius and age were negatively correlated (RC=-0.7017, -0.0225; P = 0.0144, P = 0.0111, respectively) with GAT-IOP. The seasonal effect on GAT-IOP was also significant (P < 0.0001), and in reference to winter, summer was correlated with lower GAT-IOP and spring was correlated with higher GAT-IOP (RC=-0.5133, 0.4590; P = 0.0087, P = 0.0001, respectively).

conclusionsAP was found to have a significantly positive correlation with GAT-IOP in normal healthy eyes under ordinary conditions, though the actual impact of AP on IOP in normal individuals under ordinary conditions would be minimal.

Indexed as

Atmospheric PressureGlaucomaIntraocular PressureTonometry, OcularAdultAgedAged, 80 and overFemaleHealthy VolunteersHumansJapanMaleMiddle AgedAtmospheric pressureClimatic factorsGoldmann applanation tonometryIntraocular pressure (IOP)Ordinary conditionsPopulation-based setting

Identifiers

PMID39690312
PMCPMC12149017

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.