Evidence map›Paper›PMID 39690104›Full record

ArticleThe Journal of organic chemistry2025

Expanding the Repertoire of Large Scaffolds with

Liang-Yu Chen, Udayan Chaudhury, Shengkai Wei, Junqi Li

Abstract read
In one paragraph

Article in The Journal of organic chemistry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Liang-Yu ChenDepartment of Chemistry, Iowa State University, Ames, Iowa 50011, United States.ORCID 0009-0001-6731-7358
Udayan ChaudhuryDepartment of Chemistry, Iowa State University, Ames, Iowa 50011, United States.
Shengkai WeiDepartment of Chemistry, Iowa State University, Ames, Iowa 50011, United States.
Junqi LiDepartment of Chemistry, Iowa State University, Ames, Iowa 50011, United States.ORCID 0000-0003-0336-2544

Funding

Atom-swapping reaction sequences enabled by decarbonylation and decarboxylationR35GM146854 · NIGMS · IOWA STATE UNIVERSITY · PI Junqi Li · 2022 to 2026
$1.8M
NIGMS NIH HHS R35 GM146854
6 · The paper itself

Abstract

Understanding how changes in structure translate to changes in molecular shape is key to catalyst optimization and molecular design in medicinal chemistry and materials. One key contributor to the molecular shape is the relative orientation of substituents on a scaffold. Macrocyclic metacyclophanes display their two arenes in a parallel or antiparallel fashion, resulting in

Identifiers

PMID39690104
PMCPMC12053573

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.