Evidence map›Paper›PMID 39690079›Full record

ArticleUrologic oncology2025

Patient-reported functional outcomes and treatment-related regret in Hispanic and Spanish-speaking men following prostate cancer treatment.

Andrea A Lopez, Bashir Al Hussein Al Awamlh, Li-Ching Huang, Zhiguo Zhao, Tatsuki Koyama, Karen E Hoffman, Christopher J D Wallis, Kerri Cavanaugh, Ruchika Talwar, Alicia K Morgans and 7 more

Abstract read
In one paragraph

Article in Urologic oncology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Andrea A LopezDepartment of Otolaryngology, Vanderbilt University Medical Center, Nashville, TN, USA.
Bashir Al Hussein Al AwamlhDepartment of Urology, Weill Cornell Medicine/NewYork-Presbyterian, New York, New York, USA.
Li-Ching HuangDepartment of Biostatistics, Vanderbilt University Medical Center, Nashville, TN, USA.
Zhiguo ZhaoDepartment of Biostatistics, Vanderbilt University Medical Center, Nashville, TN, USA.
Tatsuki KoyamaDepartment of Biostatistics, Vanderbilt University Medical Center, Nashville, TN, USA.
Karen E HoffmanDepartment of Radiation Oncology, The University of Texas MD Anderson Center, Houston,Texas, USA.
Christopher J D WallisDivision of Urology, Department of Surgery, University of Toronto; Mount Sinai Hospital; Department of Surgical Oncology, University Health Network, Toronto, Ontario, Canada.
Kerri CavanaughDivision of Nephrology and Hypertension, Vanderbilt University Medical Center; Vanderbilt Center for Effective Health Communication, Nashville, TN, USA.
Ruchika TalwarDepartment of Urology, Vanderbilt University Medical Center, Nashville, TN, USA.
Alicia K MorgansDepartment of Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts, USA.
Michael GoodmanDepartment of Epidemiology, Emory University Rollins School of Public Health, Atlanta, Georgia, USA.
Ann S HamiltonDepartment of Population and Public Health Sciences, Keck School of Medicine at the University of Southern California, Los Angeles, California, USA.
Xiao-Cheng WuDepartment of Epidemiology, Louisiana State University New Orleans School of Public Health, Baton Rouge, Lousiana, USA.
Jie LiCancer Epidemiology Services, New Jersey Department of Health, Rutgers Cancer Institute of New Jersey and Rutgers School of Public Health, New Brunswick, New Jersey, USA.
Brock B O'NeilDepartment of Urology, University of Utah Health, Salt Lake City, Utah, USA.
David F PensonDepartment of Urology, Vanderbilt University Medical Center; Veterans Affairs Tennessee Valley Geriatric Research Education and Clinical Center, Nashville TN, USA.
Daniel A BarocasDepartment of Urology, Vanderbilt University Medical Center, Nashville, TN, USA. Electronic address: dan.barocas@vumc.org.

Funding

10-year Comparative Effectiveness and Harms of Treatments for Prostate CancerR01CA230352 · NCI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI BAROCAS, DANIEL A · 2019 to 2023
$3.1M
Expanding Multilevel Multicomponent Mentorship in Kidney Disease ResearchK26DK138374 · NIDDK · VANDERBILT UNIVERSITY MEDICAL CENTER · PI Kerri Cavanaugh · 2023 to 2026
$562k
AHRQ HHS R01 HS019356AHRQ HHS R01 HS022640NCATS NIH HHS UL1TR000011NCI NIH HHS R01 CA230352NIDDK NIH HHS K26 DK138374
6 · The paper itself

Abstract

objectivesCompare functional outcomes and treatment-related regret over 10 years in Spanish- and English-speaking Hispanic men compared to non-Hispanic men following treatment of localized prostate cancer. METHODS AND MATERIALS: Data from a prospective cohort study of men with localized prostate cancer treated with active surveillance, radical prostatectomy or radiotherapy were used to examine the effect of survey language (Spanish speaking vs. English speaking) and ethnicity (Hispanic vs. non-Hispanic) on functional outcomes and treatment-related regret over 10 years. Outcomes were measured using validated questionaries adjusting for baseline patient and disease characteristics.

resultsA total of 770 men were included, 12% were Spanish-speaking and 12% were English-speaking Hispanic men. Compared to non-Hispanic men, Spanish-speaking Hispanic men had clinically meaningfully better urinary incontinence scores at years 3, 5 and 10 (adjusted mean difference [aMD], 12.4, 95% CI, 4.8 to 20.0; at year 10), as well as better bowel function scores at 10 years (aMD, 5.1, 95% CI 2.3 to 8.0). English-speaking Hispanic men had clinically worse urinary incontinence at 3 and 5 years (aMD, -10.7 [95% CI, -17.6 to -3.9]; at year 5) and bowel function at 10 years (aMD, -4.3 [95% CI, -8.2 to -0.4]) compared to Spanish-speaking Hispanic men. English-speaking Hispanic men were more likely to report regret than Spanish-speaking Hispanic men at 10 years (adjusted odds ratio, 7.9, 95% CI, 1.3-46.2).

conclusionsThese findings underscore the importance of considering language and ethnicity when providing counseling and support for prostate cancer survivors, emphasizing the need for personalized patient-centered care.

Indexed as

EmotionsHispanic or LatinoPatient Reported Outcome MeasuresProstatic NeoplasmsAgedHumansMaleMiddle AgedProspective StudiesTreatment OutcomeCohort studiesPatient-reported outcome measuresProspective studiesProstatic neoplasmsSurvey and questionnaires

Identifiers

PMID39690079
PMCPMC12208107

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.