Evidence map›Paper›PMID 39688755›Full record

ArticleEuropean journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology2025

An unusual case of primary pituitary abscess due to Corynebacterium pseudodiphtheriticum.

Matthew B Eustace, Li Jun Thean, Rachel A Hovelroud, Bridget E Barber

Abstract readCase Reports
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In one paragraph

Article in European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. An underestimated pathogen:Journal of clinical microbiology · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Matthew B EustaceInfectious Diseases Unit, Royal Brisbane & Women's Hospital, Cnr Butterfield St & Bowen Bridge Road, Level 6, Joyce Tweddell Building, Brisbane, QLD, 4029, Australia. m.eustace@uq.edu.au.ORCID http://orcid.org/0000-0001-7210-347X
Li Jun TheanPathology Queensland, Microbiology, Brisbane, QLD, Australia.ORCID http://orcid.org/0000-0002-6231-5265
Rachel A HovelroudEndocrinology and Diabetes Unit, Royal Brisbane & Women's Hospital, Brisbane, QLD, Australia.ORCID http://orcid.org/0009-0006-7380-3404
Bridget E BarberInfectious Diseases Unit, Royal Brisbane & Women's Hospital, Cnr Butterfield St & Bowen Bridge Road, Level 6, Joyce Tweddell Building, Brisbane, QLD, 4029, Australia.ORCID http://orcid.org/0000-0003-1066-7960

Funding

National Health and Medical Research Council 2016792
6 · The paper itself

Abstract

Pituitary abscesses are an uncommon cause of pituitary lesions. A 77-year-old woman presented for elective resection of a presumed non-functioning pituitary macroadenoma in the context of a progressive left-sided visual field deficit. She proceeded to trans-sphenoidal resection of the pituitary lesion, with purulent fluid found upon opening the pituitary capsule. Culture of operative samples yielded Corynebacterium pseudodiphtheriticum, susceptible to penicillin. Following debridement, treatment with 10-weeks of directed antimicrobials achieved good clinical response. This is the first reported case of primary C. pseudodiphtheriticum infection of the central nervous system, representing a rare but important differential for a slow growing pituitary lesion.

Indexed as

Brain AbscessCorynebacteriumCorynebacterium InfectionsPituitary DiseasesAgedAnti-Bacterial AgentsDebridementFemaleHumansMagnetic Resonance ImagingTreatment OutcomeAnti-Bacterial AgentsAntimicrobial susceptibilityCentral nervous system infectionsCorynebacterium pseudodiphtheriticumCorynebacterium speciesPituitary abscess

Identifiers

PMID39688755

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.