Evidence map›Paper›PMID 39688754›Full record

ArticleEuropean journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology2025

Pulmonary embolism in children with mycoplasma pneumonia: can it be predicted?

Jiapu Hou, Ruiyang Sun, Xue Zhang, Wanyu Jia, Peng Li, Chunlan Song

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Article in European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

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2citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

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3 · Its place in the literature

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2 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

6 authors.

Jiapu HouChildren's Hospital Affiliated to Zhengzhou University, Zhengzhou, Henan, 450052, China.
Ruiyang SunChildren's Hospital Affiliated to Zhengzhou University, Zhengzhou, Henan, 450052, China.
Xue ZhangChildren's Hospital Affiliated to Zhengzhou University, Zhengzhou, Henan, 450052, China.
Wanyu JiaChildren's Hospital Affiliated to Zhengzhou University, Zhengzhou, Henan, 450052, China.
Peng LiChildren's Hospital Affiliated to Zhengzhou University, Zhengzhou, Henan, 450052, China.
Chunlan SongChildren's Hospital Affiliated to Zhengzhou University, Zhengzhou, Henan, 450052, China. 13526867323@163.com.

Funding

Provincial-Ministerial Joint Project of Medical Science and Technology Tackling Program in Henan Province SB201903028
6 · The paper itself

Abstract

purposeTo investigate the clinical characteristics of Mycoplasma pneumoniae (MP) pneumonia (MPP) combined with pulmonary embolism (PE) in children.

methods291 hospitalized pediatric cases with MPP were enrolled from January 2018 to May 2024 and divided into the PE group (141 cases) and non-PE control group (150 cases). Clinical data of both groups were analyzed and compared.

resultsC-reactive protein (CRP), D-dimer, lactate dehydrogenase (LDH), and interleukin 6 (IL-6) were significantly higher in the PE group than in the non-PE control group. There were 85 males and 56 females in the PE group. The PE group has male-to-female ratio of 3: 2,and hemoptysis was observed in 11 children (7.08%), chest pain in 29 children (20.60%), and pulmonary necrosis in 89 children (63.12%). In the receiver operator curve(ROC), the areas under the curve(AUC) for D-dimer, CRP, IL-6, and LDH were 0.964, 0.690, 0.632, and 0.765, respectively. In the ROC curve, the cutoff values for D-dimer, CRP, IL-6, and LDH were 0.8 µg/ml, 24.2 mg/L, 37.8 pg/ml, and 461 U/L, respectively.

conclusionA proportion of children with MP infection combined with PE show atypical clinical symptoms. Children with MPP and elevated D-dimer levels, IL-6, CRP, erythrocyte sedimentation rate (ESR), and LDH may be prone to develop PE.

Indexed as

Pneumonia, MycoplasmaPulmonary EmbolismAdolescentBiomarkersChildChild, PreschoolC-Reactive ProteinFemaleFibrin Fibrinogen Degradation ProductsHumansInfantInterleukin-6L-Lactate DehydrogenaseMaleMycoplasma pneumoniaeRetrospective StudiesBiomarkersC-Reactive ProteinFibrin Fibrinogen Degradation Productsfibrin fragment DInterleukin-6L-Lactate DehydrogenaseC-reactive proteinD-dimerInterleukin 6Lactate dehydrogenaseMycoplasma pneumoniae pneumoniaPulmonary embolism

Identifiers

PMID39688754

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