Evidence map›Paper›PMID 39688645›Full record

ArticleResearch in health services & regions2024

Socioeconomic and geographic variation in adjuvant chemotherapy among elderly patients with stage III colon cancer in Norway - a national register-based cohort study.

Elin Marthinussen Gustavsen, Stig Norderval, Liv Marit Dørum, Aina Balto, Ragnhild Heimdal, Barthold Vonen, Eva Stensland, Ellinor Haukland, Beate Hauglann

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Article in Research in health services & regions, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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1citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

9 authors.

Elin Marthinussen GustavsenDepartment of Community Medicine, The Arctic University of Norway (UiT), Tromsø, Norway. elin.gustavsen@helse-nord.no.ORCID http://orcid.org/0009-0004-9936-2817
Stig NordervalDepartment of Gastrointestinal Surgery, University Hospital of Northern Norway, Tromsø, Norway.
Liv Marit DørumCancer Registry of Norway, Norwegian Institute of Public Health, Oslo, Norway.
Aina BaltoCancer Registry of Norway, Norwegian Institute of Public Health, Oslo, Norway.
Ragnhild HeimdalGeriatric Department, Akershus University Hospital, Lørenskog, Norway.
Barthold VonenNorthern Norway Regional Health Authority, Bodø, Norway.
Eva StenslandDepartment of Community Medicine, The Arctic University of Norway (UiT), Tromsø, Norway.
Ellinor HauklandDepartment of Oncology and Palliative Medicine, Nordland Hospital, Bodø, Norway.
Beate HauglannCentre for Clinical Documentation and Evaluation (SKDE), Northern Norway Regional Health Authority, Tromsø, Norway.

Funding

Helse Nord RHF HNF1567-21
6 · The paper itself

Abstract

backgroundAbout half of the patients diagnosed with colon cancer are 70 years or older. Standard treatment for stage III colon cancer is major surgical resection followed by adjuvant chemotherapy (ACT). Norwegian guidelines recommend initiation of ACT within 6 weeks after resection.

objectiveThis study investigated socioeconomic and geographic variation in the recommended provision of ACT to elderly patients with stage III colon cancer in Norway.

methodsThis population-based retrospective cohort study included patients aged 70 years or older diagnosed with stage III colon cancer between 2011 and 2021 who underwent major surgical resection. Individual data were obtained from national registries. Multilevel logistic regression analysis was used to model variation in provision of ACT.

resultsOf 4 501 included patients, 603 (13%) and 1 182 (26%) received ACT within 6 and 8 weeks after resection, respectively. The provision of ACT decreased with increasing age and frailty. Odds of ACT within 6 weeks decreased for patients with low socioeconomic status (SES) compared to high SES (odds ratio (OR) 0.67 (95% confidence interval (CI) 0.50-0.91)), and decreased for patients living alone compared to those living with a cohabitant (OR 0.72 (95% CI 0.58-0.91)). Geographic variation was found between hospital referral areas (OR 0.41-2.58).

conclusionsOur study found that ACT provision to elderly stage III colon cancer patients is associated with SES and geography, indicating variation in guidelines adherence. Further research is needed to explore the impact of ACT timing among elderly patients with stage III colon cancer in Norway.

Indexed as

Adjuvant chemotherapyColon cancerElderlyGeographic variationHealth care utilisationSocioeconomic variation

Identifiers

PMID39688645
PMCPMC11652436

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