Evidence map›Paper›PMID 39688404›Full record

ArticlemSphere2025

The transcriptional regulator Lrp activates the expression of genes involved in the biosynthesis of tilimycin and tilivalline enterotoxins in

Miguel A De la Cruz, Hilda A Valdez-Salazar, Diana Rodríguez-Valverde, Santa Mejia-Ventura, Nayely Robles-Leyva, Tania Siqueiros-Cendón, Quintín Rascón-Cruz, Nancy León-Montes, Jorge Soria-Bustos, Fernando Chimal-Cázares and 8 more

Abstract read
In one paragraph

Article in mSphere, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors.

Miguel A De la Cruz *Unidad de Investigación Médica en Enfermedades Infecciosas y Parasitarias, Centro Médico Nacional Siglo XXI, Instituto Mexicano del Seguro Social, Mexico City, Mexico.
Hilda A Valdez-Salazar *Unidad de Investigación Médica en Enfermedades Infecciosas y Parasitarias, Centro Médico Nacional Siglo XXI, Instituto Mexicano del Seguro Social, Mexico City, Mexico.
Diana Rodríguez-ValverdeUnidad de Investigación Médica en Enfermedades Infecciosas y Parasitarias, Centro Médico Nacional Siglo XXI, Instituto Mexicano del Seguro Social, Mexico City, Mexico.
Santa Mejia-VenturaUnidad de Investigación Médica en Enfermedades Infecciosas y Parasitarias, Centro Médico Nacional Siglo XXI, Instituto Mexicano del Seguro Social, Mexico City, Mexico.
Nayely Robles-LeyvaFacultad de Ciencias Químicas, Universidad Autónoma de Chihuahua, Chihuahua, Mexico.
Tania Siqueiros-CendónFacultad de Ciencias Químicas, Universidad Autónoma de Chihuahua, Chihuahua, Mexico.
Quintín Rascón-CruzFacultad de Ciencias Químicas, Universidad Autónoma de Chihuahua, Chihuahua, Mexico.
Nancy León-MontesUnidad de Investigación Médica en Enfermedades Infecciosas y Parasitarias, Centro Médico Nacional Siglo XXI, Instituto Mexicano del Seguro Social, Mexico City, Mexico.
Jorge Soria-BustosCentro de Detección Biomolecular, Benemérita Universidad Autónoma de Puebla, Puebla, Mexico.ORCID 0000-0002-1773-1657
Fernando Chimal-CázaresInstituto de Ciencias de la Salud, Universidad Autónoma del Estado de Hidalgo, Tulancingo, Hidalgo, Mexico.
Roberto Rosales-ReyesUnidad de Medicina Experimental, Facultad de Medicina, Universidad Autónoma de México, Mexico City, Mexico.
María L CedilloCentro de Detección Biomolecular, Benemérita Universidad Autónoma de Puebla, Puebla, Mexico.
Jorge A Yañez-SantosCentro de Detección Biomolecular, Benemérita Universidad Autónoma de Puebla, Puebla, Mexico.
J Antonio IbarraDepartamento de Microbiología, Escuela Nacional de Ciencias Biológicas, Instituto Politécnico Nacional, Mexico City, Mexico.ORCID 0000-0002-5016-0622
Javier TorresUnidad de Investigación Médica en Enfermedades Infecciosas y Parasitarias, Centro Médico Nacional Siglo XXI, Instituto Mexicano del Seguro Social, Mexico City, Mexico.ORCID 0000-0003-3945-4221
Jorge A GirónCentro de Detección Biomolecular, Benemérita Universidad Autónoma de Puebla, Puebla, Mexico.
James G FoxDivision of Comparative Medicine, Massachusetts Institute of Technology, Cambridge, Massachusetts, USA.ORCID 0000-0001-9307-6116
Miguel A AresUnidad de Investigación Médica en Enfermedades Infecciosas y Parasitarias, Centro Médico Nacional Siglo XXI, Instituto Mexicano del Seguro Social, Mexico City, Mexico.ORCID 0000-0003-2574-958X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The toxigenic

Indexed as

Bacterial ProteinsGene Expression Regulation, BacterialKlebsiella oxytocaLeucine-Responsive Regulatory ProteinHeLa CellsHumansOperonBacterial ProteinsLeucine-Responsive Regulatory ProteinaroXcitotoxicityKlebsiella oxytocalrpnpsA

Identifiers

PMID39688404
PMCPMC11774035

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.