Evidence map›Paper›PMID 39688329›Full record

Trial reportJournal of Korean medical science2024

Efficacy of Oral Sulfate Tablet and 2 L-Polyethylene Glycol With Ascorbic Acid for Bowel Preparation: A Prospective Randomized KASID Multicenter Trial.

Yunho Jung, Hyun Gun Kim, Dong-Hoon Yang, Hyoun Woo Kang, Jae Jun Park, Dong Hoon Baek, Jaeyoung Chun, Tae-Geun Gweon, Hyeon Jeong Goong, Min Seob Kwak and 3 more

Abstract readRandomized Controlled TrialMulticenter StudyEquivalence Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Journal of Korean medical science, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Trial
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Yunho JungDepartment of Internal Medicine, Soonchunhyang University College of Medicine, Cheonan, Korea.ORCID https://orcid.org/0000-0002-7760-0050
Hyun Gun KimDepartment of Internal Medicine, Soonchunhyang University College of Medicine, Seoul, Korea. medgun@schmc.ac.kr.ORCID https://orcid.org/0000-0001-7545-4638
Dong-Hoon YangDepartment of Gastroenterology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.ORCID https://orcid.org/0000-0001-7756-2704
Hyoun Woo KangDepartment of Gastroenterology, Seoul National University Boramae Medical Center, Seoul, Korea.ORCID https://orcid.org/0000-0003-3431-0827
Jae Jun ParkDepartment of Internal Medicine, Severance Hospital, Yonsei University College of Medicine, Seoul, Korea.ORCID https://orcid.org/0000-0001-9974-1658
Dong Hoon BaekDepartment of Internal Medicine, Pusan National University School of Medicine and Biomedical Research Institute, Pusan National University Hospital, Busan, Korea.ORCID https://orcid.org/0000-0003-1512-9475
Jaeyoung ChunDepartment of Internal Medicine, Gangnam Severance Hospital, Yonsei University College of Medicine, Seoul, Korea.ORCID https://orcid.org/0000-0002-4212-0380
Tae-Geun GweonDepartment of Internal Medicine, College of Medicine, The Catholic University of Korea, Seoul, Korea.ORCID https://orcid.org/0000-0002-0884-7228
Hyeon Jeong GoongDepartment of Internal Medicine, Soonchunhyang University College of Medicine, Bucheon, Korea.ORCID https://orcid.org/0000-0002-3388-5875
Min Seob KwakDepartment of Internal Medicine, Kyung Hee University Hospital at Gangdong, Kyung Hee University School of Medicine, Seoul, Korea.ORCID https://orcid.org/0000-0002-8988-7423
Hyun Jung LeeDepartment of Internal Medicine and Liver Research Institute, Seoul National University College of Medicine, Seoul, Korea.ORCID https://orcid.org/0000-0003-2764-9339
Soo-Kyung ParkDepartment of Internal Medicine, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine, Seoul, Korea.ORCID https://orcid.org/0000-0001-8822-9632
Jong Hoon LeeDepartment of Internal Medicine, Dong-A University College of Medicine, Busan, Korea.ORCID https://orcid.org/0000-0002-3799-3312

Funding

Soonchunhyang University 2023-0076
6 · The paper itself

Abstract

backgroundOral sulfate tablets (OSTs) are bowel preparation agents that combine oral sulfate solution and simethicone. This study compared the efficacy, tolerability, and safety of OST compared to 2 L-polyethylene glycol plus ascorbic acid (2 L-PEG/ASC).

methodsThis prospective, randomized, controlled, single-blinded, multicenter, noninferiority trial enrolled 211 healthy adults who underwent colonoscopy between May 2020 and September 2022 at 13 university hospitals. The bowel cleansing rate was assessed using the Boston Bowel Preparation Scale (BBPS) and Harefield Cleansing Scale (HCS), and the preparation agents were administered in split regimens.

resultsThe total BBPS score (8.2 ± 1.5 vs. 7.8 ± 1.4,

conclusionThe OST was not inferior to 2 L-PEG/ASC in terms of bowel cleansing efficacy and showed better tolerability when used for bowel preparation for colonoscopy.

trial registrationClinical Research Information Service Identifier: KCT0005017.

Indexed as

Ascorbic AcidCatharticsColonoscopyPolyethylene GlycolsTabletsAdministration, OralAdultFemaleHumansMaleMiddle AgedProspective StudiesSingle-Blind MethodSulfatesAscorbic AcidCatharticsPolyethylene GlycolsSulfatesTabletsBowel PreparationColonoscopyPolyethylene GlycolSulfate

Identifiers

PMID39688329
PMCPMC11650332

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.