ArticlePediatric transplantation2025
First ABO-Incompatible Pediatric Kidney Transplant in South Africa-A Case Report.
Article in Pediatric transplantation, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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Who cites it
1 citing paper in PubMed.
- ABO incompatible LRD kidney transplantation should be offered to children: results from a 33-year comparative OPTN study.Transplant international : official journal of the European Society for Organ Transplantation · 2026Article
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Authors and funding
10 authors.
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Abstract
backgroundBlood group incompatibility previously represented an obstacle to living related donor (LRD) options; desensitization modalities have expanded LRD options. ABO-incompatible kidney transplants have been successful in adults and pediatric liver transplants, but to date not yet in pediatric kidney transplants in South Africa. CASE REPORT: Patient X is a 5 year old male with end-stage kidney failure due to Posterior Urethral Valves, requiring peritoneal dialysis pre-transplant. His sister was the only suitable LRD. The recipient was blood group A+; donor was blood group B+; HLA match was 5/10, nil HLA donor specific antibodies and negative CDC and Flow crossmatches. The recipients' anti-B titer pre-transplant was a maximum of 1:8. A pre-emptive desensitization dose of Rituximab (375 mg/m
conclusionThis is the first ABO-incompatible kidney transplant in a pediatric patient in South Africa and represents an important step in expanding the pool of potential living related donors.
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