Evidence map›Paper›PMID 39688223›Full record

Observational studyANZ journal of surgery2025

Baseline characteristics of patients with degenerative cervical myelopathy in Australia: analysis from the MYelopathy NAtural History registry.

Nashwa Najib, Alper Yataganbaba, Nancy E Briggs, Ali Ghahreman, Ralph Mobbs, Prashant J Rao, Mitchell Hansen, Mark Davies, Saeed Kohan, Vinay Kulkarni and 3 more

Abstract readObservational StudyMulticenter Study
In one paragraph

Observational study in ANZ journal of surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Nashwa NajibUniversity of New South Wales (UNSW), Sydney, Australia.
Alper YataganbabaRoyal Melbourne Hospital, Melbourne, Australia.
Nancy E BriggsUniversity of New South Wales (UNSW), Sydney, Australia.
Ali GhahremanSt George Private Hospital, Sydney, Australia.
Ralph MobbsNeurospine Clinic, Sydney, Australia.
Prashant J RaoBrain and Spine Surgery, Sydney, Australia.
Mitchell HansenNewcastle Brain and Spine, Newcastle, Australia.
Mark DaviesSt George Private Hospital, Sydney, Australia.
Saeed KohanSt George Private Hospital, Sydney, Australia.
Vinay KulkarniSt George Private Hospital, Sydney, Australia.
Alisha SialUniversity of New South Wales (UNSW), Sydney, Australia.
Anuruthran AmbikaipalanEpworth Hospital, Melbourne, Australia.
Ashish D DiwanUniversity of New South Wales (UNSW), Sydney, Australia.ORCID 0000-0003-1037-8421

Funding

South Eastern Sydney Local Health District RES-ON Grant Round 2University of New South Wales (UNSW)
6 · The paper itself

Abstract

backgroundDegenerative Cervical Myelopathy (DCM) is the most common cause of non-traumatic, chronic spinal cord dysfunction worldwide, causing debilitating disability with a diminishing quality of life. The natural history of DCM is poorly understood. This is a preliminary report of the first 60 patients recruited to the MYelopathy NAtural History (MYNAH) Registry.

methodsMYNAH Registry is an investigator-initiated, multicenter, prospective, non-interventional, longitudinal, national observational study (Registry ID ACSQHC-ARCR-258). Given the observational nature of the Registry, participants' clinical management plan is neither changed nor affected. Participants are recruited via an opt-in approach. A patient with DCM diagnosed by a spine/neurosurgeon after 1st January 2018 onwards is eligible to participate regardless of their surgical status. The Patient-Reported Outcome Measures (PROMs) are NDI, EQ5D5L and EQ-VAS; and the Practitioner-Reported Outcome Measures (PrROMs) are mJOA Score and Nurick Grade.

resultsSixty participants (n = 60) have now been recruited of which male participants 34 (56.7%) and females are 26 (43.3%), with a mean age of 62.3 years (SD 14.1) and biospecimens for Proteomics have been collected from 33 (66%) participants. The median mJOA Score was 16.5 (8-18), with myelopathy severity recorded as mild in 42 (70%), moderate in 13 (21.7%) and severe in 5 (8.3%) participants. Median Nurick Grade 0 (0-5), NDI 14 (0-45), EQ5D5L Score 0.850 (-0.288-1) and EQ-VAS 70 (10-96).

conclusionsThe MYNAH National DCM Registry in Australia is a novel spinal surgical initiative, that will inform the decision(s) to proceed with the scientific, evidence-based and personalised management of DCM globally in the future.

Indexed as

Cervical VertebraeSpinal Cord DiseasesAgedAustraliaFemaleHumansLongitudinal StudiesMaleMiddle AgedPatient Reported Outcome MeasuresProspective StudiesQuality of LifeRegistriesdegenerative cervical myelopathylongitudinal cohortobservational studypatient registryprognosisstudy protocol

Identifiers

PMID39688223
PMCPMC12105558

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.