Evidence map›Paper›PMID 39686919›Full record

ArticleJournal of diabetes and metabolic disorders2025

The correlation between indirect calorimetry data and the metabolic syndrome development in men and women.

Fatemeh Roudi, Susan Darroudi, Effat Saghi, Seyed Reza Hosseini, Marzieh Kohantorabi, Alireza Rezvani, Tannaz Jamialahmadi, Amirhossein Sahebkar, Mohsen Moohebati, Majid Ghayour-Mobarhan

Abstract read
In one paragraph

Article in Journal of diabetes and metabolic disorders, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Fatemeh RoudiDepartment of Nutrition, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
Susan DarroudiInternational UNESCO Center for Health-Related Basic Sciences and Human Nutrition, Mashhad University of Medical Sciences, Mashhad, Iran.
Effat SaghiDepartment of Nutrition, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
Seyed Reza HosseiniMetabolic Syndrome Research Center, Mashhad University of Medical Sciences, Mashhad, Iran.
Marzieh KohantorabiMetabolic Syndrome Research Center, Mashhad University of Medical Sciences, Mashhad, Iran.
Alireza RezvaniMetabolic Syndrome Research Center, Mashhad University of Medical Sciences, Mashhad, Iran.
Tannaz JamialahmadiInternational UNESCO Center for Health-Related Basic Sciences and Human Nutrition, Mashhad University of Medical Sciences, Mashhad, Iran.
Amirhossein SahebkarApplied Biomedical Research Center, Mashhad University of Medical Sciences, Mashhad, Iran.
Mohsen MoohebatiCardiovascular Research Center, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
Majid Ghayour-MobarhanInternational UNESCO Center for Health-Related Basic Sciences and Human Nutrition, Mashhad University of Medical Sciences, Mashhad, Iran.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objectives: To investigate the indirect calorimetric findings in subjects with Metabolic Syndrome (MetS) compared to those without MetS and explore the potential parameters for predicting MetS in susceptible individuals. Methods: Data was collected from a cross-sectional study conducted during the second phase of The Mashhad Stroke and Heart Atherosclerotic Disorder (MASHAD) study, which involved 1,014 participants. The presence of MetS was determined using the National Cholesterol Education Program Adult Treatment Panel III criteria. The study involved taking anthropometric measurements, blood samples, and indirect calorimetry measurements. Results: The study showed significant differences in MetS criteria between the groups with and without MetS. According to the results in men, an increase in resting metabolic rate (RMR)/weight decreased the likelihood of developing MetS. However, an increase in protein oxidation raised the probability of developing MetS. Moreover, an increased RMR/weight or RMR/ body surface area (BSA) decreased the likelihood of developing MetS in women. Based on the logistic regression analysis, men with a higher RMR/Weight had a lower risk of developing MetS. Conversely, an increase in protein oxidation can increase the risk of MetS. However, women with higher RMR/Weight and RMR/BSA had a reduced risk of developing MetS. Conclusions: These findings suggest that variations in RMR and macronutrient oxidations may play a role in the development of MetS. Assessing RMR and macronutrient oxidation through indirect calorimetry could potentially be used as predictive parameters for MetS. Further research is needed to better understand the underlying mechanisms and implications of these findings.

Indexed as

Indirect calorimetryMacronutrient oxidationMetabolic syndromeResting metabolic rateRisk factors

Identifiers

PMID39686919
PMCPMC11646228

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.