Evidence map›Paper›PMID 39685787›Full record

ReviewJournal of clinical medicine2024

CT-Guided Transthoracic Core-Needle Biopsy of Pulmonary Nodules: Current Practices, Efficacy, and Safety Considerations.

Amalia Constantinescu, Emil Robert Stoicescu, Roxana Iacob, Cosmin Alexandru Chira, Daiana Marina Cocolea, Alin Ciprian Nicola, Roxana Mladin, Cristian Oancea, Diana Manolescu

Abstract readReview
In one paragraph

Review in Journal of clinical medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Amalia ConstantinescuDoctoral School, 'Victor Babes' University of Medicine and Pharmacy Timisoara, Eftimie Murgu Square 6 No. 2, 300041 Timisoara, Romania.
Emil Robert StoicescuRadiology and Medical Imaging University Clinic, Department XV, 'Victor Babes' University of Medicine and Pharmacy Timisoara, Eftimie Murgu Square No. 2, 300041 Timisoara, Romania.ORCID 0000-0003-4620-3340
Roxana IacobResearch Center for Medical Communication, 'Victor Babes' University of Medicine and Pharmacy Timisoara, Eftimie Murgu Square No. 2, 300041 Timisoara, Romania.ORCID 0000-0002-2894-712X
Cosmin Alexandru ChiraDoctoral School, 'Victor Babes' University of Medicine and Pharmacy Timisoara, Eftimie Murgu Square 6 No. 2, 300041 Timisoara, Romania.
Daiana Marina CocoleaDoctoral School, 'Victor Babes' University of Medicine and Pharmacy Timisoara, Eftimie Murgu Square 6 No. 2, 300041 Timisoara, Romania.ORCID 0009-0005-2087-6848
Alin Ciprian NicolaDoctoral School, 'Victor Babes' University of Medicine and Pharmacy Timisoara, Eftimie Murgu Square 6 No. 2, 300041 Timisoara, Romania.
Roxana MladinDoctoral School, 'Victor Babes' University of Medicine and Pharmacy Timisoara, Eftimie Murgu Square 6 No. 2, 300041 Timisoara, Romania.ORCID 0009-0001-6237-939X
Cristian OanceaCenter for Research and Innovation in Precision Medicine of Respiratory Diseases (CRIPMRD), 'Victor Babes' University of Medicine and Pharmacy Timisoara, 300041 Timisoara, Romania.ORCID 0000-0003-2083-0581
Diana ManolescuRadiology and Medical Imaging University Clinic, Department XV, 'Victor Babes' University of Medicine and Pharmacy Timisoara, Eftimie Murgu Square No. 2, 300041 Timisoara, Romania.

Funding

The APC was funded by "Victor Babes" University of Medicine and Pharmacy Timisoara.
6 · The paper itself

Abstract

CT-guided transthoracic core-needle biopsy (CT-TTNB) is a minimally invasive procedure that plays a crucial role in diagnosing pulmonary nodules. With high diagnostic yield and low complication rates, CT-TTNB is favored over traditional surgical biopsies, providing accuracy in detecting both malignant and benign conditions. This literature review aims to present a comprehensive overview of CT-TTNB, focusing on its indications, procedural techniques, diagnostic yield, and safety considerations. Studies published between 2013 and 2024 were systematically reviewed from PubMed, Web of Science, Scopus, and Cochrane Library using the SANRA methodology. The results highlight that CT-TTNB has a diagnostic yield of 85-95% and sensitivity rates for detecting malignancies between 92 and 97%. Several factors, including nodule size, lesion depth, needle passes, and imaging techniques, influence diagnostic success. Complications such as pneumothorax and pulmonary hemorrhage were noted, with incidence rates varying from 12 to 45% for pneumothorax and 4 to 27% for hemorrhage. Preventative strategies and management algorithms are essential for minimizing and addressing these risks. In conclusion, CT-TTNB remains a reliable and effective method for diagnosing pulmonary nodules, particularly in peripheral lung lesions. Advancements such as PET/CT fusion imaging, AI-assisted biopsy planning, and robotic systems further enhance precision and safety. This review emphasizes the importance of careful patient selection and procedural planning to maximize outcomes while minimizing risks, ensuring that CT-TTNB continues to be an indispensable tool in pulmonary diagnostics.

Indexed as

core-needle biopsy lungCT-guided lung biopsy efficacyCT-guided transthoracic biopsylung biopsy safetylung cancer diagnosisminimally invasive lung biopsypneumothorax in lung biopsypulmonary hemorrhage biopsypulmonary nodule diagnosistransthoracic biopsy complications

Identifiers

PMID39685787
PMCPMC11642045

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.