Evidence map›Paper›PMID 39685025›Full record

ReviewHealthcare (Basel, Switzerland)2024

The Evil Twins of Chronic Pelvic Pain Syndrome: A Systematic Review and Meta-Analysis on Interstitial Cystitis/Painful Bladder Syndrome and Endometriosis.

Alessandra Inzoli, Marta Barba, Clarissa Costa, Valeria Carazita, Alice Cola, Martina Fantauzzi, Paolo Passoni, Serena Polizzi, Matteo Frigerio

Abstract readReview
In one paragraph

Review in Healthcare (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Review
  6. Cheek acupuncture therapy combined with Chinese herbal medicine for female chronic pelvic pain: a retrospective study.Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Alessandra InzoliDepartment of Medicine and Surgery, University of Milan-Bicocca, 20126 Milano, Italy.ORCID 0000-0001-7532-3267
Marta BarbaDepartment of Gynecology, Fondazione IRCCS San Gerardo Dei Tintori, University of Milano Bicocca, Via Pergolesi 33, 20900 Monza, Italy.ORCID 0000-0002-7495-7185
Clarissa CostaDepartment of Medicine and Surgery, University of Milan-Bicocca, 20126 Milano, Italy.ORCID 0009-0009-2859-4326
Valeria CarazitaDepartment of Medicine and Surgery, University of Milan-Bicocca, 20126 Milano, Italy.
Alice ColaDepartment of Gynecology, Fondazione IRCCS San Gerardo Dei Tintori, University of Milano Bicocca, Via Pergolesi 33, 20900 Monza, Italy.
Martina FantauzziDepartment of Gynecology, Fondazione IRCCS San Gerardo Dei Tintori, University of Milano Bicocca, Via Pergolesi 33, 20900 Monza, Italy.ORCID 0000-0002-9795-5246
Paolo PassoniDepartment of Gynecology, Fondazione IRCCS San Gerardo Dei Tintori, University of Milano Bicocca, Via Pergolesi 33, 20900 Monza, Italy.
Serena PolizziDepartment of Gynecology, Fondazione IRCCS San Gerardo Dei Tintori, University of Milano Bicocca, Via Pergolesi 33, 20900 Monza, Italy.
Matteo FrigerioDepartment of Gynecology, Fondazione IRCCS San Gerardo Dei Tintori, University of Milano Bicocca, Via Pergolesi 33, 20900 Monza, Italy.ORCID 0000-0003-3952-8462

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundChronic pelvic pain is a debilitating condition affecting quality of life. Endometriosis is one of the leading causes of CPP, but recent studies highlighted the role of interstitial cystitis/bladder pain syndrome (IC/PBS) in causing CPP. Only some studies addressed the coexistence of these two conditions, which seems more frequent than what is supposed, leading to diagnostic delays and unnecessary surgeries. This systematic review aimed to evaluate the estimate of the prevalence of the comorbidity of endometriosis and IC/PBS.

methodsWe performed a systematic review of the literature indexed on PubMed, Scopus, ISI Web of Science, and Cochrane using a combination of keywords and text words represented by "painful bladder syndrome", "endometriosis", "interstitial cystitis", and "bladder pain syndrome". We performed a meta-analysis of the results.

resultsThe meta-analysis shows that the coexistence of endometriosis and IC/PBS in women with CPP ranged from 15.5% to 78.3%, which is higher than the prevalence of IC/PBS in the general population.

conclusionsPrevalence data about the coexistence of endometriosis and IC/PBS are highly heterogeneous, probably due to the paucity of available data. However, in cases of endometriosis unresponsive to treatment, other reasons for CPP (such as IC/PBS) need to be ruled out.

Indexed as

chronic pelvic painendometriosisinterstitial cystitis/bladder pain syndrome

Identifiers

PMID39685025
PMCPMC11641437

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.