Evidence map›Paper›PMID 39684943›Full record

ArticleHealthcare (Basel, Switzerland)2024

Predictors of Long COVID Among Symptomatic US Adults Testing Positive for SARS-CoV-2 at a National Retail Pharmacy.

Xiaowu Sun, Manuela Di Fusco, Laura L Lupton, Alon Yehoshua, Mary B Alvarez, Kristen E Allen, Laura Puzniak, Santiago M C Lopez, Joseph C Cappelleri

Registry-linked trialAbstract read
In one paragraph

Article in Healthcare (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05160636 (Patient-Reported Outcomes Associated With COVID-19 and Influenza), which is not on this map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05160636 active not recruitingnot on this map

Patient-Reported Outcomes Associated With COVID-19 and Influenza: A Prospective Survey Study on Outpatient Symptomatic Adults With Test-Confirmed Illness in the United States

TypeobservationalSponsorPfizerRan2022 to 2027Enrolled999ConditionsCOVID-19, Coronavirus Disease 2019, InfluenzaArmsCOVID-19 Vaccine
3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Xiaowu SunCVS Health, Woonsocket, RI 02895, USA.ORCID 0000-0002-7960-4207
Manuela Di FuscoPfizer Inc., New York, NY 10001, USA.ORCID 0000-0003-0079-7331
Laura L LuptonCVS Health, Woonsocket, RI 02895, USA.ORCID 0009-0007-3219-8815
Alon YehoshuaPfizer Inc., New York, NY 10001, USA.
Mary B AlvarezPfizer Inc., New York, NY 10001, USA.
Kristen E AllenPfizer Inc., New York, NY 10001, USA.
Laura PuzniakPfizer Inc., New York, NY 10001, USA.
Santiago M C LopezPfizer Inc., New York, NY 10001, USA.
Joseph C CappelleriPfizer Inc., New York, NY 10001, USA.ORCID 0000-0001-9586-0748

Funding

Pfizer Inc. not available
6 · The paper itself

Abstract

backgroundLong COVID remains a significant public health concern. This study investigated risk factors for long COVID in outpatient settings.

methodsA US-based prospective survey study (clinicaltrials.gov NCT05160636) was conducted in 2022 and replicated in 2023. Symptomatic adults testing positive for SARS-CoV-2 at CVS Pharmacies were recruited. CDC-based long COVID symptoms were collected at Week 4, Month 3, and Month 6 following SARS-CoV-2 testing. Logistic regression was used to develop a predictive model for long COVID using data from the 2022 cohort. The model was validated with data from the 2023 cohort. Model performance was evaluated with c-statistics.

resultsPatients characteristics were generally similar between the 2022 (N = 328) and 2023 (N = 505) cohorts. The prevalence of long COVID defined as ≥3 symptoms at Month 6 was 35.0% and 18.2%, respectively. The risk factors associated with long COVID were older age, female sex, lack of up-to-date vaccination, number of acute symptoms on the day of SARS-CoV-2 testing, increase in symptoms at Week 1, underlying comorbidities and asthma/chronic lung disease. The c-statistic was 0.79, denoting good predictive power.

conclusionsA predictive model for long COVID was developed for an outpatient setting. This research could help differentiate at-risk groups and target interventions.

Indexed as

long COVIDpredictive modelSARS-CoV-2

Identifiers

PMID39684943
PMCPMC11641684

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.