Article in International journal of molecular sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registry
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what money
Authors and funding
10 authors.
Shifa ShahidDivision of Biosciences, College of Dentistry, Ohio State University, 305 W, 12th Ave., Columbus, OH 43210, USA.ORCID 0000-0002-8794-376X
Yuanyuan HuDepartment of Biologic and Materials Sciences, School of Dentistry, University of Michigan 1011 North University, Ann Arbor, MI 48190, USA.ORCID 0009-0000-6852-8790
Fatma MohamedDivision of Biosciences, College of Dentistry, Ohio State University, 305 W, 12th Ave., Columbus, OH 43210, USA.
Lara RizzottoDivision of Biosciences, College of Dentistry, Ohio State University, 305 W, 12th Ave., Columbus, OH 43210, USA.ORCID 0000-0002-2658-9103
Michelle C LayanaDivision of Biosciences, College of Dentistry, Ohio State University, 305 W, 12th Ave., Columbus, OH 43210, USA.
Daniel T FlemingDivision of Biosciences, College of Dentistry, Ohio State University, 305 W, 12th Ave., Columbus, OH 43210, USA.ORCID 0009-0002-4540-4343
Petros PapagerakisLaboratory of Precision Oral Health and Chronobiology, Faculty of Dentistry, Laval University, Dental Medicine Pavilion, 2420, rue de la Terrasse, Quebec City, QC G1V 0A6, Canada.
Brian L FosterDivision of Biosciences, College of Dentistry, Ohio State University, 305 W, 12th Ave., Columbus, OH 43210, USA.
James P SimmerDepartment of Biologic and Materials Sciences, School of Dentistry, University of Michigan 1011 North University, Ann Arbor, MI 48190, USA.ORCID 0000-0002-7192-6105
John D BartlettDivision of Biosciences, College of Dentistry, Ohio State University, 305 W, 12th Ave., Columbus, OH 43210, USA.ORCID 0000-0003-2052-6299
Funding
Proteomics and Genetics of Enamel and DentinR01DE015846 · NIDCR · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI HU, JAN CHING CHUN · 2004 to 2019
$5.7M
Enamelysin Processing Mechanisms in AmelogenesisR01DE028297 · NIDCR · OHIO STATE UNIVERSITY · PI BARTLETT, JOHN D · 2019 to 2023
$2.7M
Identifying Novel Mechanisms for Dentoalveolar Mineralization Defects in X-linked HypophosphatemiaR01DE032334 · NIDCR · OHIO STATE UNIVERSITY · PI Brian Lee Foster · 2022 to 2026
$2.5M
Functions of extracellular matrix proteins in dental and skeletal mineralizationR01DE027639 · NIDCR · OHIO STATE UNIVERSITY · PI Brian Lee Foster · 2019 to 2026
$2.3M
National Institute of Dental and Craniofacial Research of the National Institute of Health R01DE028297 (JDB), R01DE015846 (JPS) and R01DE027639; R01DE032334 (BLF)NIDCR NIH HHS R01 DE015846NIDCR NIH HHS R01 DE027639NIDCR NIH HHS R01 DE028297NIDCR NIH HHS R01 DE032334
6 · The paper itself
Abstract
ADAM10 is a multi-functional proteinase that can cleave approximately 100 different substrates. Previously, it was demonstrated that ADAM10 is expressed by ameloblasts, which are required for enamel formation. The goal of this study was to determine if ADAM10 is necessary for enamel development. Deletion of
Indexed as
ADAM10 ProteinAmeloblastsAmyloid Precursor Protein SecretasesDental EnamelMice, KnockoutAmelogenesisAnimalsMembrane ProteinsMiceADAM10 ProteinAdam10 protein, mouseAmyloid Precursor Protein SecretasesMembrane Proteinsameloblast migrationcervical enamelCre Lox recombinationdensityhardnessmouseocclusal enamelvolume
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.
ADAM10 Expression by Ameloblasts Is Essential for Proper Enamel Formation. · full record | OpenQuestion