Evidence map›Paper›PMID 39684828›Full record

ArticleInternational journal of molecular sciences2024

Potent Anti-Cancer Activity of 1-Dehydrodiosgenone from the Product of Microbial Transformation of Steroid Saponins.

Quanshun Li, Shirong Feng, Yuanyuan Zhang, Fangyuan Mou, Ting Guo, Baofu Qin, Yihan Liu

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Quanshun LiCollege of Life Sciences, Northwest A&F University, Xianyang 712100, China.
Shirong FengCollege of Life Sciences, Northwest A&F University, Xianyang 712100, China.ORCID 0009-0005-4399-2745
Yuanyuan ZhangCollege of Life Sciences, Northwest A&F University, Xianyang 712100, China.
Fangyuan MouCollege of Life Sciences, Northwest A&F University, Xianyang 712100, China.
Ting GuoCollege of Life Sciences, Northwest A&F University, Xianyang 712100, China.
Baofu QinCollege of Life Sciences, Northwest A&F University, Xianyang 712100, China.
Yihan LiuCollege of Chemistry and Pharmacy, Northwest A&F University, Xianyang 712100, China.

Funding

the Shaanxi Province Key R&D Program 2022ZDLSF05-02
6 · The paper itself

Abstract

Steroids are extensively used in the pharmaceutical industry as industrial raw materials for the production of anti-inflammatory and anti-tumor drugs. Microbial transformation, an environmentally friendly method, displays the potential for preparing steroids on an industrial scale. In this study, four steroids, including Diosgenin, Smilagenone, Yamogenin, and 1-Dehydrodiosgenone, were isolated and identified from the solid-state fermentation (SSF) product of a novel

Indexed as

Antineoplastic AgentsApoptosisSaponinsAnimalsCell Line, TumorFusariumHumansMiceSteroidsAntineoplastic AgentsSaponinsSteroidsanti-cancer activityapoptosismicrobial transformationsafety testsolid-state fermentation

Identifiers

PMID39684828
PMCPMC11641788

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.