Evidence map›Paper›PMID 39684690›Full record

ArticleInternational journal of molecular sciences2024

Soy Protein and Safflower-Seed Oil Attenuate Inflammation and Immune Dysfunction in Rats with Hyperuricemia.

Yi-Fang Liu, Yi-Chen Wu, Yu Yang, Hui-Chen Lo

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Yi-Fang LiuDepartment of Nutritional Science, Fu Jen Catholic University, New Taipei City 242062, Taiwan.
Yi-Chen WuDepartment of Food and Nutrition, Tri-Service General Hospital, Taipei 114202, Taiwan.
Yu YangDivision of Nephrology, Internal Medicine, Changhua Christian Hospital, Changhua 500209, Taiwan.
Hui-Chen LoDepartment of Nutritional Science, Fu Jen Catholic University, New Taipei City 242062, Taiwan.ORCID 0000-0003-2138-1837

Funding

Changhua Christian Hospital 96-CCH-IPI-09
6 · The paper itself

Abstract

A plant-based diet is considered a promising approach for managing hyperuricemia (HUA). This study examined the effects of soy protein and plant-based oils on HUA-induced inflammation and immune dysfunction. Male Wistar rats, induced with HUA using oxonic acid and uric acid (UA), were fed casein or soy protein with palm or safflower oil (2 × 2 factorial design) for 8 weeks. HUA rats had lower serum albumin and T cell percentages in peripheral blood leukocytes (PBLs) and splenocytes, along with increased leukocyte counts and spleen weights, compared to healthy rats (

Indexed as

HyperuricemiaInflammationRats, WistarSafflower OilSoybean ProteinsAnimalsCytokinesMalePalm OilRatsSpleenUric AcidCytokinesPalm OilSafflower OilSoybean ProteinsUric Acidcaseincytokinehyperuricemiaimmunocyte subsetspalm oilsafflower-seed oilsoy protein

Identifiers

PMID39684690
PMCPMC11641560

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.