Evidence map›Paper›PMID 39684673›Full record

ArticleInternational journal of molecular sciences2024

2'-Hydroxycinnamaldehyde, a Natural Product from Cinnamon, Alleviates Ischemia/Reperfusion-Induced Microvascular Dysfunction and Oxidative Damage in Rats by Upregulating Cytosolic BAG3 and Nrf2/HO-1.

Yu-Hsuan Cheng, Chih-Yao Chiang, Chung-Hsin Wu, Chiang-Ting Chien

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
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  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Yu-Hsuan ChengSchool of Life Science, National Taiwan Normal University, Taipei 117, Taiwan.
Chih-Yao ChiangDepartment of Medicial Research and Division of Cardiovascular Surgery, Cardiovascular Center, Far Eastern Memorial Hospital, New Taipei City 220, Taiwan.ORCID 0000-0002-4157-6888
Chung-Hsin WuSchool of Life Science, National Taiwan Normal University, Taipei 117, Taiwan.ORCID 0000-0002-4470-2448
Chiang-Ting ChienSchool of Life Science, National Taiwan Normal University, Taipei 117, Taiwan.ORCID 0000-0001-7580-7069

Funding

Ministry of Science and Technology Council NSTC 111-2314-B-418 -011
6 · The paper itself

Abstract

2'-Hydroxycinnamaldehyde (HCA), a natural product isolated from the bark of

Indexed as

Adaptor Proteins, Signal TransducingApoptosis Regulatory ProteinsMyocardial Reperfusion InjuryNF-E2-Related Factor 2Oxidative StressRats, WistarAnimalsApoptosisBiological ProductsCinnamomum aromaticumCytosolHeme Oxygenase (Decyclizing)MaleMicrovesselsRatsUp-RegulationAdaptor Proteins, Signal TransducingApoptosis Regulatory ProteinsBAG3 protein, ratBiological ProductsHeme Oxygenase (Decyclizing)Hmox1 protein, ratNfe2l2 protein, ratNF-E2-Related Factor 22′-HydroxycinnamaldehydeapoptosisautophagyBcl-2-associated athanogene 3ferroptosismyocardial ischemia/reperfusion injurynatural product

Identifiers

PMID39684673
PMCPMC11641319

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.