Evidence map›Paper›PMID 39684669›Full record

ArticleInternational journal of molecular sciences2024

Association of Inflammasome Gene Expression Levels with Pathogenesis of Familial Mediterranean Fever in Armenians.

Varduhi Hayrapetyan, Lana Karapetyan, Lilit Ghukasyan, Sofi Atshemyan, Hovsep Ghazaryan, Valentina Vardanyan, Vahan Mukuchyan, Arsen Arakelyan, Roksana Zakharyan

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Varduhi HayrapetyanInstitute of Biomedicine and Pharmacy, Russian-Armenian University, Yerevan 0051, Armenia.
Lana KarapetyanInstitute of Biomedicine and Pharmacy, Russian-Armenian University, Yerevan 0051, Armenia.
Lilit GhukasyanLaboratory of Human Genomics, Institute of Molecular Biology of the National Academy of Sciences of the Republic of Armenia (NAS RA), Yerevan 0014, Armenia.
Sofi AtshemyanInstitute of Biomedicine and Pharmacy, Russian-Armenian University, Yerevan 0051, Armenia.
Hovsep GhazaryanInstitute of Biomedicine and Pharmacy, Russian-Armenian University, Yerevan 0051, Armenia.
Valentina VardanyanDepartment of Rheumatology, Yerevan State Medical University after Mkhitar Heratsi (YSMU), Yerevan 0025, Armenia.
Vahan MukuchyanNairi Medical Center, Yerevan 0015, Armenia.
Arsen ArakelyanInstitute of Biomedicine and Pharmacy, Russian-Armenian University, Yerevan 0051, Armenia.
Roksana ZakharyanInstitute of Biomedicine and Pharmacy, Russian-Armenian University, Yerevan 0051, Armenia.ORCID 0000-0003-3411-7584

Funding

Armenian Engineers and Scientists of America (AESA) N/AScience Committee of the MESCS of Armenia 21SCG-1F010Science Committee of the MESCS of Armenia 23AA-1F035
6 · The paper itself

Abstract

Familial Mediterranean fever (FMF) is a genetically determined autoinflammatory disease transmitted mostly by an autosomal recessive mechanism and caused by point mutations of the

Indexed as

Familial Mediterranean FeverInflammasomesNLR Family, Pyrin Domain-Containing 3 ProteinPyrinAdolescentAdultArmeniaCase-Control StudiesCaspase 1Eastern European PeopleFemaleGene Expression RegulationHumansMaleMiddle AgedYoung AdultCaspase 1InflammasomesMEFV protein, humanNLR Family, Pyrin Domain-Containing 3 ProteinNLRP3 protein, humanPyrinFamilial Mediterranean fevergene expressionimmunityinflammasomeMEFV gene

Identifiers

PMID39684669
PMCPMC11641286

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.