Evidence map›Paper›PMID 39684650›Full record

ArticleInternational journal of molecular sciences2024

Genetic Diversity Analysis and Identification of Candidate Genes for Growth Traits in Chengkou Mountain Chicken.

Lingbin Liu, Yi Wang, Yu Huang, Zhen Wang, Qigui Wang, Haiwei Wang

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Lingbin LiuChongqing Academy of Animal Sciences, Rongchang, Chongqing 402460, China.ORCID 0000-0001-9266-9868
Yi WangCollege of Animal Science and Technology, Southwest University, Beibei, Chongqing 400715, China.
Yu HuangCollege of Animal Science and Technology, Southwest University, Beibei, Chongqing 400715, China.
Zhen WangChongqing Academy of Animal Sciences, Rongchang, Chongqing 402460, China.
Qigui WangChongqing Academy of Animal Sciences, Rongchang, Chongqing 402460, China.
Haiwei WangChongqing Academy of Animal Sciences, Rongchang, Chongqing 402460, China.

Funding

Chongqing Modern Agricultural Industry Technology System (Poultry) CQMAITS202314Special Key Project of Chongqing Technology Innovation and Application Development cstc2021jscx-gksbX0004, CSTB2023TIAD-LUX0003Special Project for Performance Incentive and Guidance of Scientific Research Institutions in Chongqing cstc2022jxj180018
6 · The paper itself

Abstract

Growth traits constitute critical factors in the breeding program of broiler chickens. The Chengkou mountain chicken A-lineage (CMC-A) represents a breed specifically bred for meat production. To further explore the growth performance of the CMC-A population, this study conducted whole-genome sequencing on 464 CMC-A roosters to systematically evaluate their genetic diversity. Additionally, runs of homozygosity (ROH) islands and genome-wide association studies (GWASs) were employed to identify the loci and functional genes influencing the growth traits in Chengkou mountain chickens. The results revealed a high level of genetic diversity and low levels of inbreeding in Chengkou mountain chickens. Several genes associated with stress resistance, muscle growth, and fat deposition were pinpointed through ROH island identification. Moreover, 52 SNP loci were detected, along with 71 candidate genes. These findings enhance our understanding of the genetic architecture underlying the growth traits in Chengkou mountain chickens and provide a theoretical foundation for subsequent breeding endeavors.

Indexed as

ChickensGenetic VariationGenome-Wide Association StudyPolymorphism, Single NucleotideAnimalsBreedingHomozygotePhenotypeQuantitative Trait LociWhole Genome Sequencingcandidate genesChengkou mountain chickengenome-wide association studies (GWASs)growth traits

Identifiers

PMID39684650
PMCPMC11641596

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.