Evidence map›Paper›PMID 39684473›Full record

ArticleInternational journal of molecular sciences2024

Analysis of CD1a-Positive Monocyte-Derived Cells in the Regional Lymph Nodes of Patients with Gallbladder Cancer.

Sachiko Maeda, Keita Kai, Kanako Kawasaki, Tomokazu Tanaka, Takao Ide, Hirokazu Noshiro

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Sachiko MaedaDepartment of Pathology & Microbiology, Faculty of Medicine, Saga University, Saga 849-8501, Japan.
Keita KaiDepartment of Pathology, Saga University Hospital, Saga 849-8501, Japan.ORCID 0000-0003-1553-2598
Kanako KawasakiDepartment of Pathology & Microbiology, Faculty of Medicine, Saga University, Saga 849-8501, Japan.
Tomokazu TanakaDepartment of Surgery, Faculty of Medicine, Saga University, Saga 849-8501, Japan.
Takao IdeDepartment of Surgery, Faculty of Medicine, Saga University, Saga 849-8501, Japan.
Hirokazu NoshiroDepartment of Surgery, Faculty of Medicine, Saga University, Saga 849-8501, Japan.

Funding

Japan Society for the Promotion of Science 22K16913Soda Toyoji Memorial Foundation JS20220057
6 · The paper itself

Abstract

Dendritic cells (DCs) are known to be major antigen-presenting cells, and lymph nodes (LNs) play an important role in DC-mediated immune response. CD1a is known as a marker of monocyte-derived DCs. The present study focused on the infiltration of CD1a-positive DCs (CD1a-DCs) into regional LNs in 70 cases of gallbladder cancer (GBC). After univariate analyses, the results showed that LN infiltration by CD1a-DCs was associated with unfavorable clinical outcomes in patients with GBC, with all cases categorized in the CD1a-DCs high group had nodal metastasis. LN infiltration by CD1a-DCs was not an independent prognostic factor identified by multivariate analyses. After subgroup analyses of cases with LN metastasis (

Indexed as

Antigens, CD1Dendritic CellsGallbladder NeoplasmsLymphatic MetastasisLymph NodesMonocytesAdultAgedFemaleHumansMaleMiddle AgedPrognosisAntigens, CD1CD1a antigenCD1adendritic cellgallbladder cancerlymph nodemonocyte

Identifiers

PMID39684473
PMCPMC11641552

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.