ArticleInternational journal of molecular sciences2024
NS2B-D55E and NS2B-E65D Variations Are Responsible for Differences in NS2B-NS3 Protease Activities Between Japanese Encephalitis Virus Genotype I and III in Fluorogenic Peptide Model.
Article in International journal of molecular sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registry
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Abdul WahaabShanghai Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Shanghai 200241, China.ORCID 0000-0002-1919-3653
Yan ZhangShanghai Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Shanghai 200241, China.ORCID 0000-0003-2216-5749
Ke LiuShanghai Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Shanghai 200241, China.
Jason L RasgonThe Department of Entomology, Center for Infectious Disease Dynamics, and the Huck Institutes of the Life Sciences, Pennsylvania State University, University Park, PA 16802, USA.ORCID 0000-0002-4050-8429
Lei KangShanghai Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Shanghai 200241, China.
Muddassar HameedShanghai Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Shanghai 200241, China.
Chenxi LiShanghai Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Shanghai 200241, China.
Muhammad Naveed AnwarShanghai Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Shanghai 200241, China.ORCID 0000-0002-4762-1635
Yanbing ZhangShanghai Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Shanghai 200241, China.ORCID 0009-0003-9564-3999
Anam ShoaibSchool of Behavioral and Brain Sciences, University of Texas at Dallas, Richardson, TX 75080, USA.
Beibei LiShanghai Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Shanghai 200241, China.ORCID 0000-0002-4134-4024
Yafeng QiuShanghai Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Shanghai 200241, China.ORCID 0000-0003-4211-0817
Jianchao WeiShanghai Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Shanghai 200241, China.ORCID 0000-0002-3246-6273
Zhiyong MaShanghai Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Shanghai 200241, China.
Funding
JLR was supported by NIH grant R01AI12820.The National Key Research and Development Program of China awarded to Y.Q No. 2022 YFD 1800100The project of Cooperation on Animal Biosecurity Prevention and Control in Lancang and Mekong Countries awarded to J.W. No. 125161035The Project of Shanghai Science and Technology Commission awarded to Z.M No. 22N41900400The Shanghai Municipal Science and Technology Major Project awarded to Z.M No. ZD2021CY001The study was supported by the National Natural Science Foundation of China awarded to ZM No. 32273096
6 · The paper itself
Abstract
Japanese encephalitis virus (JEV) NS2B-NS3 is a protein complex composed of NS3 proteases and an NS2B co-factor. The N-terminal protease domain (180 residues) of NS3 (NS3(pro)) interacts directly with a central 40-amino acid hydrophilic domain of NS2B (NS2B(H)) to form an active serine protease. In this study, the recombinant NS2B(H)-NS3(pro) proteases were prepared in
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.
NS2B-D55E and NS2B-E65D Variations Are Responsible for Differences in NS2B-NS3 Protease Activities Between Japanese Encephalitis Virus Genotype I and III in Fluorogenic Peptide Model. · full record | OpenQuestion